ArticleRespirology (Carlton, Vic.)2025
Microplastics in Human Bronchoalveolar Lavage Fluid.
Article in Respirology (Carlton, Vic.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence on microplastic exposure and respiratory health outcomes: a systematic review.Therapeutic advances in respiratory diseasePooled it
- Microplastics in Human Thoracic Tissues: Increased Burden in Patients with Lung Malignancy.Journal of clinical medicine · 2026Article
- Microplastics and Nanoplastics in the Human Diet: Sources of Exposure, Bioavailability, Toxicokinetics, and Systemic Health Effects.Molecules (Basel, Switzerland) · 2026Review
- Nanoplastic Pollution of Human Bronchoalveolar Lavage Probed Based on Tip-Enhanced Raman Scattering.Sensors (Basel, Switzerland) · 2026Article
- Respiratory risks of microplastics and nanoplastics: Where? What? How?Innovation (Cambridge (Mass.)) · 2026Review
- Effects of microplastics in CPAP users: looking for needles in the haystack?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Identification of human exposure to airborne micro-plastics and its potential effects utilizing bronchoalveolar lavage (BAL) fluid.Bioinformation · 2026Article
- Microplastics in Human Bronchoalveolar Lavage Fluid.Respirology (Carlton, Vic.) · 2025Article
Corrections and comments
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Authors and funding
21 authors.
Funding
Abstract
BACKGROUND AND
objectiveHealth impacts of inhaling airborne microplastics have been actively investigated. Although microplastics have been detected in lung tissues and bronchoalveolar lavage fluids, their detection requires substantial effort and is technically challenging, with existing studies demonstrating various limitations. Bronchoalveolar lavage fluid is a less invasive sampling method than surgical lung biopsy. This study aimed to establish a detection method for microplastics from bronchoalveolar lavage fluid and evaluate the relevant health impacts.
methodsPatients undergoing bronchoscopy for diffuse lung disease diagnosis were included. Microplastics were detected using Nile Red staining and fluorescence microscopy. Particle size, shape, and concentration were assessed through image analysis, and plastic types were identified via Raman spectroscopy. Correlations between microplastic findings and clinical laboratory data were evaluated.
resultsMicroplastics were detected in the bronchoalveolar lavage fluid of all 30 patients. The median concentration of Nile Red-stained particles was 684.7 particles/mL, and over 80.0% of the particles were smaller than 10 μm, with 93.5% being particulate and 6.5% fibre. The most frequently identified microplastics were polyvinyl chloride, polystyrene, and polyethylene terephthalate. Microplastic concentration positively correlated with blood C-reactive protein levels (r
conclusionsWe established a method for detecting microplastics in bronchoalveolar lavage fluid. Microplastics were found in all patients, with a potential link to inflammation. In addition, Nile Red staining was applied for the first time to detect plastics in the lung and appeared to be useful for screening and quantification.
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