Evidence map›Paper›PMID 40843953›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Early cognitive ability and dementia risk: Response to Chen and colleagues.

William S Kremen, Malin Ericsson, Margaret Gatz, Ida K Karlsson, Marianne Nygaard, Nancy L Pedersen, Matthew S Panizzon

Abstract readLetter
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

William S KremenDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Malin EricssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Margaret GatzCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Ida K KarlssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Marianne NygaardDepartment of Public Health, The Danish Twin Registry, University of Southern Denmark, Odense, Denmark.
Nancy L PedersenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Matthew S PanizzonDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.

Funding

The VETSA Longitudinal Twin Study of Cognition and Aging (VETSA 4)R01AG050595 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELMAN, JEREMY A, FRANZ, CAROL ELAINE · 2015 to 2024
$28.0M
The VETSA Longitudinal MRI Twin Study of Aging (VETSA MRI 4)R01AG076838 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE, Jeremy A Elman · 2022 to 2026
$8.7M
Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortiumR01AG060470 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2018 to 2022
$3.6M
Differences in the association of education with ADRD across countries, historical eras, and men and women.R01AG081248 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DEBORAH G FINKEL, Brian K. Finch · 2024 to 2026
$3.6M
NIA NIH HHS R01 AG050595NIA NIH HHS R01 AG060470NIA NIH HHS R01 AG076838NIA NIH HHS R01 AG081248NIH HHS R01AG050595NIH HHS R01AG060470NIH HHS R01AG076838NIH HHS R01AG081248Swedish Research Council 2021-00180
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alzheimer's diseaseeducationoccupational complexityreverse causationrisk predictionYoung adult general cognitive ability

Identifiers

PMID40843953
PMCPMC12371434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.