Evidence map›Paper›PMID 40843803›Full record

ArticleEuropean burn journal2025

Post-Traumatic Stress Disorder (PTSD) Is Associated with Increased Physical Skin Symptom Burden Following Severe Burn Injuries: Subgroup Analysis of a Multicenter Prospective Cohort.

Felix J Klimitz, Martin Aman, Hubert Neubauer, Annette Stolle, Hans Ziegenthaler, Tobias Niederegger, Adriana C Panayi, Gabriel Hundeshagen, Ulrich Kneser, Leila Harhaus

Abstract read
In one paragraph

Article in European burn journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Felix J KlimitzDepartment of Surgery, Division of Plastic Surgery, Yale School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0002-1278-0505
Martin AmanDepartment of Hand, Replantation, and Microsurgery, BG Trauma Center Berlin, Chair of Hand, Replantation, and Microsurgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Hubert NeubauerDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany.ORCID 0000-0002-0765-4790
Annette StolleDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany.ORCID 0000-0002-1063-7510
Hans ZiegenthalerRehabilitation Center, Graefliche Kliniken-Moritz Klinik GmbH, 07639 Bad Klosterlausnitz, Germany.
Tobias NiedereggerDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany.ORCID 0009-0004-3065-4352
Adriana C PanayiDepartment of Hand, Replantation, and Microsurgery, BG Trauma Center Berlin, Chair of Hand, Replantation, and Microsurgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Gabriel HundeshagenDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany.
Ulrich KneserDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071 Ludwigshafen, Germany.ORCID 0000-0002-3402-2860
Leila HarhausDepartment of Hand, Replantation, and Microsurgery, BG Trauma Center Berlin, Chair of Hand, Replantation, and Microsurgery, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.

Funding

Deutsche Gesetzliche Unfallversicherung FR-268
6 · The paper itself

Abstract

backgroundSevere burn injuries often lead to lasting physical and psychological consequences. Post-traumatic stress disorder (PTSD) is common among burn survivors and may be influenced by persistent somatic complaints. This study examined whether PTSD is associated with a higher burden of physical symptoms during and after inpatient rehabilitation.

methodsWe conducted a subgroup analysis of a multicenter prospective cohort study involving 103 adult burn patients in inpatient rehabilitation. Based on Impact of Event Scale-Revised (IES-R) scores and clinical evaluation, patients were grouped as PTSD (n = 43) or No PTSD (n = 60). Physical symptoms assessed included skin dryness (xerosis), temperature sensitivity (cold/heat), numbness, skin tightness, and increased sweating.

resultsPatients with PTSD reported significantly more physical symptoms at follow-up than those without PTSD: xerosis (74% vs. 50%,

conclusionPTSD is associated with a higher and more persistent burden of physical skin symptoms after severe burns. These findings underscore the importance of early PTSD screening and integrated psychological-somatic rehabilitation to improve long-term recovery and quality of life.

Indexed as

burn injuriesphysical symptomspost-traumatic stress disorder (PTSD)psychosomatic interactionsquality of liferehabilitation

Identifiers

PMID40843803
PMCPMC12372007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.