Evidence map›Paper›PMID 40843802›Full record

ArticleEuropean burn journal2025

Pilot Study on Resuscitation Volume's Effect on Perfusion and Inflammatory Cytokine Expression in Peri-Burn Skin: Implications for Burn Conversion.

Tamer R Hage, Edward J Kelly, Eriks Ziedins, Babita Parajuli, Cameron S D'Orio, David M Burmeister, Lauren Moffatt, Jeffrey W Shupp, Bonnie C Carney

Abstract read
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In one paragraph

Article in European burn journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tamer R HageFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.
Edward J KellyFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.ORCID 0009-0001-6475-9089
Eriks ZiedinsFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.
Babita ParajuliDepartments of Medicine and Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Cameron S D'OrioFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.ORCID 0000-0002-1162-9440
David M BurmeisterDepartments of Medicine and Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.ORCID 0000-0002-1256-0158
Lauren MoffattFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.
Jeffrey W ShuppFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.
Bonnie C CarneyFirefighter's Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Nicole Ann Errett · 1995 to 2026
$42.5M
CDMRP W81WH-19-2-0004NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

Fluid resuscitation after thermal injury is paramount to avoid burn shock and restore organ perfusion. Both over- and under-resuscitation can lead to unintended consequences affecting patient outcomes. While many studies have examined systemic effects, limited data exist on how fluid resuscitation impacts burn wound progression in the acute period. Furthermore, the mechanisms underlying burn wound progression remain not fully understood. This study used a swine model to investigate how varying resuscitation levels affect peri-burn wound dynamics. Twenty-seven female Yorkshire pigs were anesthetized, subjected to 40% total body surface area burn and 15% hemorrhage, then randomized (

Indexed as

burn wound progression (BWP)fluid resuscitationlaser doppler imaging (LDI)skin inflammationterminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)

Identifiers

PMID40843802
PMCPMC12372052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.