A case of multiorgan IgG4-related disease with coronary artery vasculitis: Review of the 2019 Rheumatologic Classification Guidelines and what radiologists need to know.

Jasmine Zhao, Asmar Ghani, Ali Mohammadzadeh, Cato Chan, James Shi

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Abdominal manifestations of multisystem diseases: a pattern-based imaging review.Abdominal radiology (New York) · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jasmine ZhaoDepartment of Radiology, University of California Irvine, University of California Irvine Medical Center, Orange, CA, USA.

Asmar GhaniDepartment of Radiology, University of California Irvine, University of California Irvine Medical Center, Orange, CA, USA.

Ali MohammadzadehDepartment of Radiology, University of California Irvine, University of California Irvine Medical Center, Orange, CA, USA.

Cato ChanDepartment of Radiology, University of California Irvine, University of California Irvine Medical Center, Orange, CA, USA.

James ShiDepartment of Radiology, University of California Irvine, University of California Irvine Medical Center, Orange, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a rare fibroinflammatory disorder with diverse manifestations that can affect nearly any organ system. This case report describes a 58-year-old man presenting with obstructive jaundice due to a biliary stricture concerning for cholangiocarcinoma; however, eventual pathology, serology and imaging findings confirmed IgG4-RD. Over 2 years, the disease progressed to involve multiple organs, including 3-vessel coronary arteritis, a serious but underrecognized manifestation that may present with the ``pigs-in-a-blanket" sign on imaging. Despite treatment, the patient ultimately suffered a fatal cardiac event soon after. This case underscores the importance of recognizing characteristic imaging features, particularly those outlined in the 2019 American College of Rheumatology/European League Against Rheumatism classification criteria, which can act as a framework for radiologists and clinicians in early diagnosis. Prompt recognition, multidisciplinary collaboration, and timely treatment are essential to avoid unnecessary surgical interventions and reduce the risk of life-threatening complications.

Indexed as

Autoimmune pancreatitisCoronary arteritisIgG4-related diseaseRenal diseaseRetroperitoneal fibrosisSclerosing cholangitis

Identifiers

PMID40843301

DOI10.1016/j.radcr.2025.07.022

PMCPMC12365821

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