Evidence map›Paper›PMID 40843278›Full record

ArticleTransboundary and emerging diseases2025

Evolution and Spread of Y280-Lineage H9N2 Low Pathogenicity Avian Influenza Viruses in Korea, 2020-2023.

Andrew Y Cho, Tae-Hyeon Kim, Heesu Lee, Sun-Hak Lee, Yeram Seo, Bitgoeul Kim, Chung-Young Lee, Sungsu Youk, Jung-Hoon Kwon, Chang-Seon Song and 1 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrew Y ChoAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-2918-2349
Tae-Hyeon KimAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Heesu LeeAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Sun-Hak LeeAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0960-0550
Yeram SeoAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Bitgoeul KimDepartment of Microbiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Chung-Young LeeDepartment of Microbiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID https://orcid.org/0000-0003-3037-7581
Sungsu YoukDepartment of Microbiology, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea.ORCID https://orcid.org/0000-0002-3106-3712
Jung-Hoon KwonLaboratory of Veterinary Microbiology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID https://orcid.org/0000-0002-6737-2242
Chang-Seon SongAvian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4158-6402
Dong-Hun LeeWildlife Health Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0820-7378

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2020, Y280-lineage H9N2 low pathogenic avian influenza was detected in South Korea for the first time. Active surveillance from live bird markets (LBMs) and farms revealed the continuous circulation of Y280-lineage H9N2 viruses, replacing the previously indigenous Y439-lineage and becoming dominant in South Korea. Antigenic mapping showed a substantial antigenic difference between the Y280 and Y439-lineage viruses. Bayesian phylodynamic approach suggests the introduction of Y280-lineage viruses from China and revealed the frequent exchange of viruses between LBM and farms. The presence of mammalian adaptation markers and high binding affinity to human-type sialic acid receptor raise a concern on interspecies transmission of the viruses to mammals. These findings underscore the importance of continued genomic surveillance to monitor the evolution of H9N2 viruses and assessment of zoonotic potential.

Indexed as

Influenza A Virus, H9N2 SubtypeInfluenza in BirdsPoultry DiseasesAnimalsBirdsChickensEvolution, MolecularPhylogenyRepublic of Korea

Identifiers

PMID40843278
PMCPMC12367370

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.