SynthesisFrontiers in neurology2025
Effects of high-intensity exercise on rehabilitation of patients after stroke: a systematic review and meta-analysis of randomized controlled trials with high quality.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The effect of high-intensity interval training on cardiorespiratory fitness for non-ambulatory stroke survivors: a randomized controlled trial.Frontiers in sports and active living · 2026Trial
- High-Intensity Interval Training on Cardiorespiratory Fitness, Cognitive Function, and Functional Capacity in Adults with Stroke: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Potential Mechanisms of Exercise-Mediated Ferroptosis Regulation in Central Nervous System Diseases.Molecular neurobiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To present the latest systematic review and meta-analysis of high-quality randomized controlled trials (RCTs) comparing high-intensity exercise with routine rehabilitation in stroke patients. Methods: PubMed, Web of Science, and Cochrane were used to searching literature up to October 2024. RCTs with sample size of ≥50 individuals were included. Primary outcomes assessed were the Six-Minute Walking Test (6MWT), Ten-Meter Walk Test (10MWT), VO Results: Seven RCTs with 724 participants were included. Meta-analysis revealed significant improvements in the 6MWT (SMD: 0.28; 95% CI: 0.11, 0.45) and BBS (SMD: 0.35; 95% CI: 0.03, 0.67) in the high-intensity exercise group. However, high-intensity exercise had no significant effect on VO Conclusion: High-intensity exercise significantly improves 6MWT and BBS in stroke patients, but does not significantly affect TUG, VO Systematic review registration: CRD42024623036 Publicly accessible URL: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024623036.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.