Evidence map›Paper›PMID 40843238›Full record

ArticleThe Journal of clinical and aesthetic dermatology2025

Comparison of Colony-forming Units of

Carlos Daniel Sánchez-Cárdenas, Liliana Godinez Aldrete, Zaira Ruelas Guzmán, Diana Carolina Vega Sánchez, Mayra Itzel Cano Viveros, Nancy Pulido Díaz, Roberto Arenas, Gabriela Moreno-Coutiño

Abstract read
PubMed Full text at PMC
In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlos Daniel Sánchez-CárdenasDrs. Sánchez-Cárdenas, Aldrete, Guzmán, Viveros, and Díaz are with the Dermatology Service at the La Raza National Medical Center in Mexico City, Mexico.
Liliana Godinez AldreteDrs. Sánchez-Cárdenas, Aldrete, Guzmán, Viveros, and Díaz are with the Dermatology Service at the La Raza National Medical Center in Mexico City, Mexico.
Zaira Ruelas GuzmánDrs. Sánchez-Cárdenas, Aldrete, Guzmán, Viveros, and Díaz are with the Dermatology Service at the La Raza National Medical Center in Mexico City, Mexico.
Diana Carolina Vega SánchezDrs. Sánchez, Arenas, and Moreno-Coutiño are with the Mycology Service at the General Hospital Dr. Manuel Gea González in Mexico City, Mexico.
Mayra Itzel Cano ViverosDrs. Sánchez-Cárdenas, Aldrete, Guzmán, Viveros, and Díaz are with the Dermatology Service at the La Raza National Medical Center in Mexico City, Mexico.
Nancy Pulido DíazDrs. Sánchez-Cárdenas, Aldrete, Guzmán, Viveros, and Díaz are with the Dermatology Service at the La Raza National Medical Center in Mexico City, Mexico.
Roberto ArenasDrs. Sánchez, Arenas, and Moreno-Coutiño are with the Mycology Service at the General Hospital Dr. Manuel Gea González in Mexico City, Mexico.
Gabriela Moreno-CoutiñoDrs. Sánchez, Arenas, and Moreno-Coutiño are with the Mycology Service at the General Hospital Dr. Manuel Gea González in Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt has been proposed that some cases of refractory atopic dermatitis are caused by an overgrowth of

methodsThis prospective, cross-sectional, and comparative study was conducted in patients with AD who were treated with prednisone, cyclosporine, and methotrexate, and separated in two groups, those with and those without response to their treatments, and who had not received treatment with antifungals (topical or systemic) within the prior six months. Scoring Atopic Dermatitis (SCORAD) was determined to evaluate disease severity and therapy response. A sample of epidermal cells from the glabellar region was obtained by scraping for direct examination with methylene blue and m-Dixon agar culture in search of colony-forming units. Fisher's exact test and Mann-Whitney U test were performed to compare the groups.

resultsA total of 15 patients were included in each group. The majority of the group who were refractory to treatment were women (60%), while the non-refractory group were predominantly men (66.7%). In addition, 73.3 percent of subjects with therapeutic resistance presented fungal growth in the cultures compared to 40 percent in the non-resistant group. A significant difference was found between direct examination (

conclusionPatients with AD resistant to systemic treatment had a higher count of colony-forming units of

Indexed as

Atopic dermatitiscolony-forming unitMalassezia spprefractory systemic treatment

Identifiers

PMID40843238
PMCPMC12367241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.