Can the Pursuit of an Ageless Face Redefine Medicine? Exploring Dermatology's Role in the Quest for Immortality.

Aaron Cheng, Harrison Shawa, Zachary Uttke, David G Cotter

Abstract readReview

In one paragraph

Review in The Journal of clinical and aesthetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aaron ChengMr. Cheng is with the Long School of Medicine at the University of Texas Health San Antonio in San Antonio, Texas.

Harrison ShawaDr. Shawa is with the Division of Dermatology at the Department of Internal Medicine at Washington University in St. Louis in St. Louis, Missouri.

Zachary UttkeMr. Uttke is with the Department of Molecular Biology, Cell Biology, and Biochemistry at Brown University and the Warren Alpert Medical School of Brown University in Providence, Rhode Island.

David G CotterDr. Cotter is with Las Vegas Dermatology and the University of Nevada Las Vegas School of Medicine in Las Vegas, Nevada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent years have witnessed significant growth in aging research due to groundbreaking discoveries in gerotherapeutics and an ever-increasing interest in longevity. Such advances beg the question, what if the physical and functional declines we associate with aging were no longer inevitable, but instead treatable through the next frontier of medical innovation? In this article, we explore the broader social and ethical implications of advancing healthspan and mitigating age-related decline. We also highlight dermatology's unique role as a catalyst of aging research, serving as a model for integrating aesthetic and functional innovations. Finally, we discuss the curious role and the ethical challenges of the aesthetic dermatology industry in the healthspan debate.

Indexed as

aestheticsAgingethicsgerotherapeuticshealthspan

Identifiers

PMID40843234

PMCPMC12367245

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.