Correlation between Neurotransmitter Transporter Gene Variants and Childhood Autism Spectrum Disorder: A Case-control Study.

Chen Shen, Limeng Shen, Fei Qu, Chenye He, Hong Yu, Zengyu Zhang, Jun Liu

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Article in Saudi journal of medicine & medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chen ShenDepartment of Clinical Laboratory, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Limeng ShenDepartment of Clinical Laboratory, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Fei QuDepartment of Clinical Laboratory, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Chenye HeDepartment of Clinical Laboratory, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Hong YuDepartment of Clinical Psychology, Xiaoshan First Affiliated Hospital, Hangzhou Normal University, Hangzhou, China.

Zengyu ZhangDepartment of Pediatrics, Xiaoshan First Affiliated Hospital, Hangzhou Normal University, Hangzhou, China.

Jun LiuDepartment of Clinical Laboratory, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This case-control study aimed to determine the correlation between single nucleotide polymorphisms (SNPs) in the neurotransmitter transporter genes Patients and Methods: Children with ASD and age- and sex-matched healthy controls were recruited from a hospital and schools, respectively. Seven SNPs in the Results: A total of 249 children with ASD and 343 controls were included. The genotype frequencies of the examined SNPs were not correlated with childhood ASD. Only the T allele of the SNP rs140700 displayed a non-significant association with a reduced risk of childhood ASD (OR = 0.6, 95% CI: 0.4-1.0, Conclusion: Certain SNPs on neurotransmitter transporter

Indexed as

Autism spectrum disorderneurotransmitter transportersingle nucleotide polymorphismSLC6A3SLC6A4

Identifiers

PMID40843231

DOI10.4103/sjmms.sjmms_106_25

PMCPMC12366910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.