Evidence map›Paper›PMID 40843137›Full record

ArticleChina CDC weekly2025

An Outbreak of Isoniazid-Resistant Tuberculosis in a School Originating from Household Transmission - Guigang City, Guangxi Zhuang Autonomous Region, China, November 2024.

Da Xu, Xiaoyan Liang, Lingyun Zhou, Wei Chen, Jing Ye, Juan Li, Weihua Yao, Jinhui Zhu, Zhezhe Cui

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Da Xu *Institute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Xiaoyan Liang *Institute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Lingyun Zhou *Institute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Wei ChenChinese Field Epidemiology Training Program, Chinese Centre for Disease Control and Prevention, Beijing, China.
Jing YeInstitute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Juan LiInstitute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Weihua YaoGuigang City Center for Disease Control and Prevention, Guigang City, Guangxi Zhuang Autonomous Region, China.
Jinhui ZhuGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.
Zhezhe CuiInstitute of Tuberculosis Control and Prevention, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning City, Guangxi Zhuang Autonomous Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Tuberculosis (TB) represents one of the world's most significant infectious diseases, caused by What is added by this report?: This outbreak investigation identified 18 TB cases (15 students, 1 teacher, and 2 staff members), including 5 cases with isoniazid-resistant TB. Sixteen pulmonary TB cases demonstrated clear epidemiological linkage, indicating a clustered outbreak spanning multiple households, school grades, and both junior and senior high schools. What are the implications for public health practice?: This outbreak underscores the critical importance of comprehensive household contact screening. When tuberculosis emerges within a family unit, school contacts - particularly students and teachers - require immediate and thorough screening. Additionally, the outbreak reveals significant gaps in the effectiveness and quality of entrance physical examinations that demand urgent improvement.

Indexed as

Isoniazid resistantOutbreaks in a schoolTuberculosis

Identifiers

PMID40843137
PMCPMC12365653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.