ArticleJournal of physics. Complexity2025
Time-varying synergy/redundancy dominance in the human cerebral cortex.
Article in Journal of physics. Complexity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Charting higher-order models of brain function beyond pairwise interactions.Nature communications · 2026Article
- Structural signatures of synergy and redundancy in human brain function.bioRxiv : the preprint server for biology · 2026Article
- Leveraging multivariate information for community detection in functional brain networks.Communications biology · 2025Article
- Revealing non-trivial information structures in aneural biological tissues via functional connectivity.PLoS computational biology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Recent work has emphasized the ubiquity of higher-order interactions in brain function. These interactions can be characterized as being either redundancy or synergy-dominated by applying tools from multivariate information theory. Though recent work has shown the importance of both synergistic and redundant interactions to brain function, their dynamic structure is still unknown. Here we analyze the moment-to-moment synergy and redundancy dominance of the fMRI BOLD signal during rest for 95 unrelated subjects to show that redundant and synergistic interactions have highly structured dynamics across many interaction sizes. The whole brain is strongly redundancy-dominated, with some subjects never experiencing a whole-brain synergistic moment. In small sets of brain regions, our analyses reveal that subsets which are redundancy dominated on average exhibit the most complex dynamic behavior as well as the most synergistic and most redundant time points. In accord with previous work, these regions frequently belong to a single coherent functional system, and our analysis reveals that they become synergistic when that functional system becomes momentarily disintegrated. Although larger subsets cannot be contained in a single functional network, similar patterns of instantaneous disintegration mark when they become synergistic. At all sizes of interaction, we find notable temporal structure of both synergy and redundancy-dominated interactions. We show that the interacting nodes change smoothly in time and have significant recurrence. Both of these properties make time-localized measures of synergy and redundancy highly relevant to future studies of behavior or cognition as time-resolved phenomena.
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Registered trials
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