Evidence map›Paper›PMID 40843073›Full record

ArticleFrontiers in pediatrics2025

Construction of a prediction model for pneumonia in children undergoing neurosurgery based on regular clinical laboratory tests and baseline information.

Shumei Zhang, Hongyao Wang, Shuting Lin, Yihuang Zhang, Yingbin Lin, Wenhua Fang, Yue Chen

Abstract read
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Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shumei Zhang *Department of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Hongyao Wang *Department of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Shuting LinDepartment of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yihuang ZhangDepartment of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yingbin LinDepartment of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Wenhua FangDepartment of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yue ChenDepartment of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Pneumonia is a common complication in children undergoing neurosurgery, leading to prolonged length of stay as well as increased hospital expenses. A prediction model for pneumonia in children undergoing neurosurgery based on common laboratory indicators is an effective clinical measure for early intervention in high-risk patients. In this study, we proposed to construct a pneumonia prediction model for children undergoing neurosurgery by selecting routine baseline characteristics and laboratory indicators. Methods: This study retrospectively collected children admitted from January 2021 to April 2025. The data collected included common clinical baseline data and regular laboratory test results. Variables were filtered by multivariate regression and constructed a prediction model. Results: Screening revealed that whether emergency admission, whether surgical treatment, type of disease, serum creatinine level and neutrophil count were statistically different indicators. A prediction model was constructed based on the above indicators, and the C-statistic values of the model were 0.835 (test set, 95% CI: 0.7692-0.9006) and 0.716 (validation set, 95% CI: 0.5803-0.8509), which were satisfactory. And a clinically usable nomogram based on the above model was constructed. Conclusions: Hospital-acquired pneumonia is a common complication in children undergoing neurosurgery and may be related to a variety of factors. Using basic clinical baseline data and laboratory data to monitor and detect high-risk patients in the early stages of the disease is a useful clinical attempt that deserves further exploration.

Indexed as

childrenneurosurgeryprediction model establishmentpulmonary infectionrisk factor analysis

Identifiers

PMID40843073
PMCPMC12364629

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.