Evidence map›Paper›PMID 40843065›Full record

ArticleCureus2025

Comprehensive Assessment of the Vecta46 Intermediate Catheter for Neurovascular Interventions.

Alan Napole, Georgios Sioutas, Pierce Davis, Chethan Reddy, Saarang Patel, Sandeep Kandregula, Sneha S Mannam, Rashad Jabarkheel, Kyle W Scott, Oleg Shekhtman and 2 more

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alan NapoleNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Georgios SioutasNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Pierce DavisNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Chethan ReddyNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Saarang PatelNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Sandeep KandregulaNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Sneha S MannamNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Rashad JabarkheelNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Kyle W ScottNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Oleg ShekhtmanNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Jan-Karl BurkhardtNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Visish M SrinivasanNeurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Advancements in neuroendovascular surgery with sophisticated catheters have enhanced outcomes in complex procedures. The FDA-approved Vecta46 intermediate catheter (IMC) by Stryker Corporation (Kalamazoo, MI) is used in various neurovascular interventions. Since its approval, the Vecta46 IMC has not been comprehensively studied. This study evaluates its safety, versatility, and efficacy in real-world multi-pathology applications. Methods We retrospectively reviewed 53 patients who underwent endovascular procedures with the Vecta46 IMC. We collected and analyzed demographic details, baseline characteristics, procedural specifics, and clinical outcomes. Results Among 53 cases, common comorbidities included hypertension (n = 25, 47.2%) and hyperlipidemia (n = 22, 41.5%). Antiplatelet use was noted in 43.4% (n = 23), and anticoagulant use in 13.2% (n = 7). Aneurysm treatments accounted for 56.6% (n = 30) of cases, followed by middle meningeal artery (MMA) embolization for chronic subdural hematomas (cSDHs) (18.9%) (n = 10), stroke thrombectomies (11.3%) (n = 6), Onyx embolization for dural arteriovenous fistulas (dAVFs) (7.5%) (n = 4), and arteriovenous malformations (AVMs) (5.7%) (n = 3). Flow diversion was the most common aneurysm treatment (56.7%) (n = 17). Most procedures were transradial (79.2%) (n = 42), primarily on the right side (88.7%) (n = 47), with verapamil used in 75.5% (n = 40). The mean number of vessels selected was 3.2±1.9, procedure duration was 102.4±66.8 minutes, fluoroscopy time was 43.6±31.1 minutes, contrast dose was 80.5±31.6 mL, and reference air kerma was 2114.0±1349.4 mGy. The Vecta46 was successfully navigated to the target vessel in 96.2% (n = 51) of cases. Intraprocedural complications included a nontarget vessel embolization, a thromboembolic event, and a non-flow-limiting focal dissection. No hemorrhagic complications or vessel irregularities occurred in the Vecta46 region. Post-procedural complications were minimal, with only forearm edema and an access site hematoma. Conclusions The Vecta46 catheter is an effective and safe tool for endovascular procedures, demonstrating versatility and reliability in neurovascular interventions.

Indexed as

endovascularneuroendovascular surgeryneurosurgeryneurovascularvecta46

Identifiers

PMID40843065
PMCPMC12366675

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.