Evidence map›Paper›PMID 40843051›Full record

ArticleOxford medical case reports2025

Hemorrhagic brain metastasis as the initial presentation of osteosarcoma: a rare case report.

Salma El Aouadi, Rania Bouanane, Soukaina Bahha, Imane Iraqui, Asaad El Bakkari, F Z Laamrani, Youssef Omor, Rachida Latib, Sanae Amalik

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salma El AouadiDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Rania BouananeDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Soukaina BahhaDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Imane IraquiPathology Department, Ibn Sina University Hospital Center, Avenue Ibn Rochd, Agdal District, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Asaad El BakkariDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
F Z LaamraniDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Youssef OmorDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Rachida LatibDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.
Sanae AmalikDepartment of Radiology, National Institute of Oncology, Ibn Sina University Hospital Center, Avenue Allal El Fassi, Quartier des Orangers, Rabat 10000, Rabat-Salé-Kénitra Region, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is the most common malignant bone tumor in children and adolescents, with a predilection for long bones and frequent pulmonary metastases. Brain metastases are rare, occurring in 1.8% to 5.6% of cases, and hemorrhagic ones are exceptionally uncommon, with only a few cases documented in the literature. We report the case of a 16-year-old girl who presented with acute headache and seizures. Imaging revealed hemorrhagic brain and pulmonary metastases, and biopsy confirmed a primary femoral osteosarcoma. This case represents an exceptionally rare presentation of osteosarcoma and highlights its aggressive metastatic behavior.

Indexed as

hemorrhagic brain metastasesosteosarcomapediatric oncologypulmonary metastases

Identifiers

PMID40843051
PMCPMC12365974

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.