Was an aortic valve replacement with a mechanical valve the right option all along? Cogan's syndrome with recurrent aortic regurgitation: a case of evolving surgical decisions.

Maram Gad, Lanya Faiq, Emma Arifagic, Alex Kamougeros, Stelios Ioannou, George Shiakos, Ioannis Tzanavaros

Abstract readCase Reports

In one paragraph

Article in Oxford medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maram GadEuropean University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.ORCID https://orcid.org/0009-0008-8236-2924

Lanya FaiqEuropean University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.

Emma ArifagicEuropean University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.ORCID https://orcid.org/0009-0000-8845-9905

Alex KamougerosApollonion Private Hospital, Cardiac Innovation Center, Nicosia, Cyprus.

Stelios IoannouAdult and Pediatric Cardiac Surgery Department, Cardiac Innovation Center of Apollonion Private Hospital, Nicosia, Cyprus.

George ShiakosEuropean University Cyprus, School of Medicine, 6 Diogenous Street, Nicosia, Engomi 2404, Cyprus.

Ioannis TzanavarosAdult and Pediatric Cardiac Surgery Department, Cardiac Innovation Center of Apollonion Private Hospital, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cogan Syndrome (CS) is a rare autoimmune disease, complicated by a variety of cardiac manifestations. This case report represents the only documented case in the Republic of Cyprus. It describes the experience of a 23- year-old woman with CS who presented with newly diagnosed, severe aortic regurgitation (AR) and suspected endocarditis. The patient was initially treated successfully with a Ross procedure, but the recurrence of acute AR a few years later, led to the decision to treat her with a mechanical valve replacement, minimising complications and providing as permanent of a surgical solution as possible. This case demonstrates the importance of individualising treatment for such patients.

Indexed as

Audiovestibular medicinecardiology and cardiovascular systemsimmunologymedical ophthalmologyrheumatology

Identifiers

PMID40843044

DOI10.1093/omcr/omaf143

PMCPMC12365956

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