Evidence map›Paper›PMID 40842929›Full record

ArticleFrontiers in human neuroscience2025

Cognitive constraints and lexicogrammatical variability in ASD: from diagnostic discriminators to intervention strategies.

Sumi Kato, Kazuaki Hanawa

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sumi KatoDepartment of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan.
Kazuaki HanawaNatural Language Processing Lab, Graduate School of Information Sciences, Tohoku University, Sendai, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study examines whether specific lexicogrammatical features can reliably differentiate individuals with autism spectrum disorder (ASD) from non-ASD individuals. Classification models using logistic regression and deep neural networks (DNN) demonstrated high performance-80% accuracy, 82% precision, 73% sensitivity, and 87% specificity. To clarify which linguistic variables contribute to this differentiation, the analysis focused on identifying key syntactic features associated with ASD-specific patterns of lexicogrammatical choices. Methods: This study used the Tag Linear Model, developed in prior work, which enables identification of specific lexicogrammatical discriminators. Although DNN models achieved higher predictive accuracy, their internal processes were not interpretable. To identify statistically significant features, we applied a logistic regression with 10,000 bootstrap iterations; Results: Of the 135 lexicogrammatical items analyzed, 46 were identified asstatistically significant discriminators ( Discussion: These findings suggest that syntactic variation in ASD reflects underlying domain-specific cognitive constraints. Linking lexicogrammatical features to cognitive-functional domains provides a linguistically grounded perspective on the neurocognitive profiles of ASD and informs future diagnostic and intervention approaches.

Indexed as

autism spectrum disorder (ASD)corpusdiagnostic assessmentlexicogrammatical discriminatormachine learningnatural language processing (NLP)systemic functional linguistics (SFL)

Identifiers

PMID40842929
PMCPMC12366435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.