ArticleBrain communications2025
Striatal dopaminergic patterns and clinical features in frontotemporal dementia.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- A frontotemporal dementia-like phenotype in schizophrenia: links to striatal dopamine and iron accumulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Observational
- Neuropsychiatric Symptoms in Primary Progressive Aphasia: Phenomenology, Circuits, and Clinical Management.Current neurology and neuroscience reports · 2026Review
- Article
- Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias.Nature aging · 2026Article
- Incidence of primary progressive aphasia in Salento, Italy: a population-based study.Alzheimer's research & therapy · 2026Article
- Executive function and the feasibility of clinical trials for frontotemporal dementia.The Lancet regional health. Europe · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frontotemporal dementia is a group of neurodegenerative disorders mainly characterized by behavioural and language impairments. While the precise pathophysiology remains elusive, emerging evidence points to an important role of dopamine dysfunction, particularly within the caudate nucleus. Moreover, a theoretical model proposes that frontotemporal dementia manifestations result from a deficit in goal-directed behaviour, which may be related to altered dopamine control of the frontostriatal circuitry. However, no study has investigated the gradient of striatal dopamine transporter levels in frontotemporal dementia using neuroimaging and their correlation with clinical features. This study used
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.