Evidence map›Paper›PMID 40842796›Full record

ArticleCureus2025

Low Rates of Early Aseptic Loosening of the Cemented Attune S+ Total Knee Arthroplasty System.

McKenna Sheridan, Pranav Krishnan, Hassan Farooq, Whisper Grayson, Harold Rees, Nicholas Brown

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

McKenna SheridanOrthopaedic Surgery, Loyola University Stritch School of Medicine, Maywood, USA.
Pranav KrishnanOrthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, USA.
Hassan FarooqOrthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, USA.
Whisper GraysonOrthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, USA.
Harold ReesOrthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, USA.
Nicholas BrownOrthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Aseptic loosening is a common cause of late revision surgery performed following total knee arthroplasty (TKA). Recent advances in implant designs have aimed at reducing this risk, with the cemented Attune S+ total knee system focused on improving stability through enhanced cement adherence. Despite excellent preliminary in vitro data, there is a lack of clinical studies assessing the performance of this implant, with prior studies reporting high rates of aseptic loosening. The primary objective of this study was to assess the clinical outcomes, primarily rates of aseptic loosening and revision, of Attune S+ implants. Methodology This retrospective study included 47 patients who underwent TKA using the cemented Attune S+ system between November 2017 and April 2023. All surgeries were performed by a single fellowship-trained arthroplasty surgeon at a tertiary care academic medical center. The primary outcome was aseptic loosening, which was evaluated on postoperative knee radiographs for stress shielding and radiolucent lines. Results There were no patients with radiographic evidence of aseptic loosening, and no known revision surgeries were performed. Of note, one patient had a subsequent operation 817 days after the original TKA to remove scar tissue in the knee joint due to arthrofibrosis, but no signs of prosthetic failure were found intraoperatively. Conclusions In this study, there were no cases of aseptic loosening or revision surgery observed with the cemented Attune S+ TKA system.

Indexed as

aseptic looseningattune total knee systemcemented total knee arthroplastycomplicationstotal knee arthroplasty (tka)

Identifiers

PMID40842796
PMCPMC12365711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.