Evidence map›Paper›PMID 40842780›Full record

ReviewCureus2025

Exploring Variability in Spinal Anesthesia Levels Achieved During Cesarean Section Deliveries: A Narrative Review.

Naresh Paliwal, Imran Ahmed Khan

Registry-linked trialAbstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07638280 (Analysis of Non-pharmacological Factors on Spinal Anaesthesia Block Duration), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07638280 recruitingnot on this mapstarted 2026, after this paper: background citation

Analysis of Non-pharmacological Factors on Spinal Anaesthesia Block Duration

TypeobservationalSponsorTaksim Egitim ve Arastirma HastanesiRan2026 to 2026Enrolled140ConditionsParaspinal Muscle Mass and Spinal AnaesthesiaArmsspinal anaesthesia
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Naresh PaliwalAnesthesiology, Dr. Panjabrao Deshmukh Memorial Medical College, Amravati, IND.
Imran Ahmed KhanCommunity Medicine, KMC Medical College and Hospital, Maharaj Ganj, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal anesthesia (SA) is the preferred technique for cesarean section (CS), but variability in sensory block levels poses challenges. This variability becomes particularly prominent in pregnant women, and while the physiological changes of pregnancy are widely recognized contributors, local anesthetic (LA) properties and some technical factors are also responsible for these variations. Literature from 2015 to 2025 was reviewed on PubMed and Google Scholar to identify physiological, technical, and pharmacological factors responsible for spinal block characteristics in parturients. Pregnancy-related changes, e.g., reduced cerebrospinal fluid volume (CSF), technical factors (e.g., interspace misidentification), and drug baricity contribute to variability. A detailed understanding of the physiological changes of pregnancy, fine details of anesthetic technique, and pharmacological properties of medications used is important. Individualized techniques and adopting ultrasound guidance could enhance consistency. Further studies on CSF density and standardized protocols are warranted.

Indexed as

bupivacainecesarean sectionhead-down tiltpregnancyspinal anesthesia

Identifiers

PMID40842780
PMCPMC12366537

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.