Evidence map›Paper›PMID 40842755›Full record

ArticleCureus2025

A Case of Intramural Adenosarcoma With Sarcomatous Overgrowth Associated With Adenomyosis and Endometriosis.

Kyohei Kitamura, Sachiko Minamiguchi, Hiroaki Ito, Yosuke Yamada, Yuki Himoto, Koji Yamanoi, Ken Yamaguchi, Hironori Haga

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyohei KitamuraDepartment of Diagnostic Pathology, Kyoto Katsura Hospital, Kyoto, JPN.
Sachiko MinamiguchiDepartment of Diagnostic Pathology, Fujita Health University Hospital, Toyoake, JPN.
Hiroaki ItoDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, JPN.
Yosuke YamadaDepartment of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, JPN.
Yuki HimotoDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, JPN.
Koji YamanoiDepartment of Obstetrics and Gynecology, Kyoto University Graduate School of Medicine, Kyoto, JPN.
Ken YamaguchiDepartment of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JPN.
Hironori HagaDepartment of Diagnostic Pathology, Kyoto University Hospital, Kyoto, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosarcoma is a mixed epithelial and mesenchymal neoplasm composed of a malignant mesenchymal component and a benign Müllerian glandular component. Although the endometrium is the most common primary site, adenosarcoma can also occur in the cervix, ovaries, fallopian tubes, vagina, or other sites outside the genital tract. This report presents the case of a 59-year-old woman with intramural adenosarcoma, associated with adenomyosis and endometriosis. Initially, a 4.0-cm uterine mass was identified via magnetic resonance imaging (MRI), and a watchful waiting approach was adopted. However, the mass grew to 8.5 cm over three months. A pathological examination revealed a polypoid mass with malignant spindle cells and benign glandular epithelium, confirming adenosarcoma with sarcomatous overgrowth. The endometrium showed no abnormalities, and the tumor appeared contiguous with adenomyosis and endometriosis in the myometrium and serosa of the uterine corpus, respectively. This case highlights the importance of considering adenosarcoma in the differential diagnosis of malignant transformation from adenomyosis or endometriosis.

Indexed as

adenomyosisadenosarcomaendometriosissarcomatous overgrowthuterus

Identifiers

PMID40842755
PMCPMC12366477

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.