ArticleCureus2025
Impact of Blood Volume on Pathogen Detection and Time to Positivity in Paediatric Blood Cultures Using BACT/ALERT 3D Automated Systems.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Situation and questions regarding the practice of blood cultures in paediatric patients: an opinion paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Bloodstream infections (BSIs) are a major cause of morbidity and mortality in paediatric populations. Early and accurate pathogen detection is crucial for prompt therapy. Blood volume is a key factor influencing culture sensitivity and time to positivity (TTP). This study evaluated the impact of blood volume on microbial recovery and TTP in paediatric blood cultures using the BACT/ALERT 3D automated system (bioMérieux, Marcy-l'Étoile, France). Methods In this prospective study (April 2023-September 2024), 160 paediatric blood culture bottles were analysed. Blood volume was calculated using pre- and post-inoculation weights. Bottles were classified as optimal (>0.5 mL) or suboptimal (<0.5 mL). TTP and pathogen recovery were compared. Results Among 160 paediatric blood cultures, 78 (48.75%) flagged positive. Coagulase-negative
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.