Evidence map›Paper›PMID 40842555›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2025

Neighborhood social cohesion and Alzheimer's disease dementia risk in South Asians in the United States.

Lilah M Besser, Preeti P Zanwar, Oanh L Meyer, Elizabeth K Sohn, Irene H Yen, Namratha R Kandula, Alka M Kanaya

Abstract read
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In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lilah M BesserComprehensive Center for Brain Health, Department of Neurology, University of Miami Miller School of Medicine, 7700 W. Camino Real, Suite 200, Boca Raton, FL 33433, United States.
Preeti P ZanwarTexas A&M University Irma Lerma Rangel School of Pharmacy, Kingsville & College Station, TX, 78363; Jefferson College of Population Health, Thomas Jefferson University, Philadelphia, PA, 19107.
Oanh L MeyerAlzheimer's Disease Research Center, Department of Neurology, University of California, Davis School of Medicine, 1651 Alhambra Blvd., Suite 200A, Sacramento, CA, 95817.
Elizabeth K SohnCenter for Effective Philanthropy, 675 Massachusetts Avenue, 11 floor, Cambridge, MA 02139.
Irene H YenPublic Health Department, School of Social Sciences, Humanities & Arts, 5200 N. Lake Road, Merced, CA 95343.
Namratha R KandulaNorthwestern University, Feinberg School of Medicine, Department of Medicine, Division of General Internal Medicine, Chicago, IL.
Alka M KanayaUniversity of California, San Francisco; Departments of Medicine, Epidemiology & Biostatistics.

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Mediators of Atherosclerosis in South Asians Living in AmericaR01HL093009 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2010 to 2018
$5.4M
Longitudinal associations between neighborhood greenspace and brain aging in cognitively normal older adultsK01AG063895 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BESSER, LILAH · 2020 to 2024
$628k
Associations between neighborhood environments across the life course and Alzheimer's disease and related dementia outcomes among Hispanic older adults born in and outside the USR21AG089003 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BESSER, LILAH · 2024 to 2025
$435k
Objectively measured neighborhood greenness in midlife and late life cognitive and brain imaging outcomes for Alzheimer's disease: The Multi-Ethnic Study of AtherosclerosisR21AG075291 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BESSER, LILAH · 2022 to 2022
$379k
NCRR NIH HHS UL1 RR024131NHLBI NIH HHS R01 HL093009NIA NIH HHS K01 AG063895NIA NIH HHS R21 AG075291NIA NIH HHS R21 AG089003
6 · The paper itself

Abstract

introductionLittle is known about whether neighborhood social and built environments influence Alzheimer's disease (AD) dementia risk in South Asians.

methodsWe used data on 745 South Asians living in the US who were ≥40-years old. Neighborhood characteristics included percentage of Asian residents, Walk Score (walkability), and neighborhood social cohesion. We calculated an AD dementia risk score from age, gender, education, diabetes, hypertension, current smoking, low high-density lipoprotein, and high waist-to-hip ratio. Multivariable linear regression examined associations between neighborhood characteristics and AD dementia risk scores; interaction terms tested for differences by gender.

resultsGreater neighborhood social cohesion was associated with lower AD dementia risk scores in the overall sample. Stratifying by gender, the beneficial association was only observed for women and not men (interaction p-value: 0.01).

conclusionPolicies and interventions promoting neighborhood social cohesion may help reduce AD dementia risk among South Asian middle and older-age women in the US.

Indexed as

Alzheimerdementiagenderneighborhoodsocial cohesionsocial determinants of healthSouth Asian

Identifiers

PMID40842555
PMCPMC12367061

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.