ArticleFrontiers in medicine2025
A novel Mxene-SPR-based sensor for sensing different types of cancers.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Early-stage cancer screening benefits from optical transducers capable of reading minute refractive-index deviations in biofluids. This work models a surface-plasmon-resonance (SPR) biosensor that stacks copper, silicon nitride, and MXene in Kretschmann geometry and evaluates its response to six tumour-related refractive-index increments (Δn = 0.014-0.024 RIU). Transfer-matrix calculations guide a layer-by-layer optimisation: 40 nm Cu, 7 nm Si₃N₄, and two MXene sheets form the best-balanced configuration (Sys₃), while a single MXene layer on 45 nm Cu (Sys₄) offers an alternative with lower optical loss. The optimised MXene sensors raise angular sensitivity to 254° RIU
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