Evidence map›Paper›PMID 40842488›Full record

ArticleJournal of surgical case reports2025

Lung cancer metastasis to the breast in patients with breast implants-first reports in the literature.

Chloe Jordan, Sarah Al-Hamali, Krzysztof Sosnowski, Laura Henderson, Susanna Polotto, Areeg Abbas, Georgette Oni

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In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chloe JordanAddenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, United Kingdom.ORCID https://orcid.org/0000-0003-4827-5882
Sarah Al-HamaliSchool of Medicine, University of Nottingham, East Block, Lenton, Nottingham NG7 2UH, United Kingdom.
Krzysztof SosnowskiSchool of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0SP, United Kingdom.
Laura HendersonAddenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
Susanna PolottoSchool of Medicine, University of Nottingham, East Block, Lenton, Nottingham NG7 2UH, United Kingdom.
Areeg AbbasDepartment of Histopathology, Nottingham University Hospitals, NHS Trust, Nottingham NG5 1PB, United Kingdom.
Georgette OniAddenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing use of breast implants in cosmetic and reconstructive surgery has brought attention to rare malignancies linked to the capsule that forms around them, such as breast implant-associated anaplastic large cell lymphoma, angiosarcomas and breast implant associated-squamous cell carcinoma. While breast metastasis from primary lung cancer is rare, it has not been previously reported in patients with breast implants. This case series presents two unique cases. The first involves a 46-year-old woman with left breast implants presenting with breast and axillary lumps and was diagnosed with contralateral small cell lung carcinoma . The second case features a 73-year-old woman with prior bilateral breast cancer and implant reconstruction, who presented with right breast swelling and was diagnosed with subsequent metastatic squamous cell carcinoma of the lung. Metastatic disease to the breast from a lung primary in patients with breast implants remains a rare and unreported phenomenon. This case series contributes to the literature by presenting two unique cases of metastatic lung cancer in patients with breast implants, both of whom presented primarily with breast-related symptoms. The chronic inflammation caused by breast implants may create a conducive environment for tumour growth and dissemination. Further research is critical for identification of pathogenesis and its prevention in future cases.

Indexed as

breast implantsbreast metastasislung cancerreconstructive surgery

Identifiers

PMID40842488
PMCPMC12366779

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.