ArticleJournal of surgical case reports2025
Lung cancer metastasis to the breast in patients with breast implants-first reports in the literature.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
The increasing use of breast implants in cosmetic and reconstructive surgery has brought attention to rare malignancies linked to the capsule that forms around them, such as breast implant-associated anaplastic large cell lymphoma, angiosarcomas and breast implant associated-squamous cell carcinoma. While breast metastasis from primary lung cancer is rare, it has not been previously reported in patients with breast implants. This case series presents two unique cases. The first involves a 46-year-old woman with left breast implants presenting with breast and axillary lumps and was diagnosed with contralateral small cell lung carcinoma . The second case features a 73-year-old woman with prior bilateral breast cancer and implant reconstruction, who presented with right breast swelling and was diagnosed with subsequent metastatic squamous cell carcinoma of the lung. Metastatic disease to the breast from a lung primary in patients with breast implants remains a rare and unreported phenomenon. This case series contributes to the literature by presenting two unique cases of metastatic lung cancer in patients with breast implants, both of whom presented primarily with breast-related symptoms. The chronic inflammation caused by breast implants may create a conducive environment for tumour growth and dissemination. Further research is critical for identification of pathogenesis and its prevention in future cases.
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