ArticleInternational journal of STD & AIDS2026
Thinking beyond the tablet: Acceptability of different HIV-PrEP modalities among GBMSM and gender-diverse individuals having sex with men in the UK.
Article in International journal of STD & AIDS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620730 (PrEP-LANA), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PrEP-LANA (Pre-exposure Prophylaxis- Long-acting Novel Antiviral Agent)
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundHIV-PrEP is a key component of HIV combination prevention and has been routinely available through oral formulations (i.e. oral tablets) across sexual health services (SHSs) in the UK since 2020. We used data from a large, online community survey to assess the acceptability and preference of different HIV-PrEP modalities among gay, bisexual, and other men who have sex with men (GBMSM) and gender-diverse individuals living in the UK.MethodsUsing data collected from the 'Reducing inequalities in Sexual Health' (RiiSH) survey, an online community survey of 1106 GBMSM and gender-diverse individuals having sex with men (November/December 2023), we performed a secondary analysis examining HIV-PrEP modality acceptability and preference (e.g. oral, long acting injectable, gel, or patch) (%) by HIV-PrEP history (never, in lookback period of last 3-4 months since survey completion). Where ≥2 modalities were indicated, participants were asked to specify a single preferred modality. Single choice options were assumed to be the preferred HIV-PrEP modality.ResultsIrrespective of HIV-PrEP history, long acting injectables were highly acceptable (>70%) and the preferred modality (58% [222/386] by those never having used HIV-PrEP, 73% [75/103] in those without HIV-PrEP use in the lookback, 74% [314/424] in those with HIV-PrEP use in the lookback).ConclusionsWe found high acceptability of the use of injectables, with general preference over oral tablets. If injectable HIV-PrEP becomes available at SHSs in England, these modalities could have positive impacts on HIV-PrEP delivery, use, and access.
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