Evidence map›Paper›PMID 40842121›Full record

ArticleBrain and behavior2025

The Prognostic Value of Inflammatory Indexes in Patients With Severe Traumatic Brain Injury.

Yongxiang Yang, Dongbo Zou, Chen Yin, Xiansong Zhu, Yunxing Li, Yuan Ma, Jingmin Cheng

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongxiang YangDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Dongbo ZouDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Chen YinDepartment of Gerontology, Sichuan Lansheng Brain Hospital, Chengdu, China.
Xiansong ZhuDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Yunxing LiDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Yuan MaDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.ORCID https://orcid.org/0000-0003-4311-7105
Jingmin ChengDepartment of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.ORCID https://orcid.org/0009-0002-1981-8921

Funding

National Natural Science Foundation of China 82101465Natural Science Foundation of Sichuan Province 2022NSFSC1444
6 · The paper itself

Abstract

objectiveThis study aims to investigate whether the inflammatory indexes including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), and systemic inflammatory indexes (SIIs) can prognosis the outcome of patients with severe traumatic brain injury (sTBI).

methodsA total of 118 sTBI patients were retrospectively recruited from June 2015 to June 2024. First, the clinical data including baseline clinical features, hematological indexes at 1/3/7 days after hospital admission, were collected, and the Glasgow Coma Scale (GCS) at 3 months after discharge was recorded. Then, the absolute value of SII, NLR, PLR and LMR was calculated, and the prognostic value of them was further analyzed via comparative, relevant, and regression statistical methods.

resultsCompared to sTBI patients in the favorable outcome group, the absolute value of white blood cell (WBC) and neutrophil at 1/3/7 days, and the absolute value of monocyte at 1 day and NLR at 3 days after admission was higher in sTBI patients of the unfavorable outcome group. ROC curve and multivariate logistic regression analysis indicated that NLR at 3 days after admission was an independent prognostic factor for GOS in patients with sTBI.

conclusionsNLR at 3 days after admission might be a new, accurate, and objective inflammatory index, which had prognostic value in the clinical outcome prediction for patients with sTBI.

Indexed as

Brain Injuries, TraumaticInflammationAdultAgedFemaleGlasgow Coma ScaleHumansLeukocyte CountLymphocytesMaleMiddle AgedMonocytesNeutrophilsPrognosisRetrospective Studiesclinical outcomeGOSinflammatory indexsevere traumatic brain injury

Identifiers

PMID40842121
PMCPMC12370831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.