Evidence map›Paper›PMID 40841893›Full record

SynthesisBMC surgery2025

Risk factors of axial symptoms after posterior cervical spine surgery: a meta-analysis.

Ke Zhang, Zhencheng Xiong, Yuhao Zhang, Ziyi Zhuang, Sizhen Zhan, Mingsheng Tan, Ping Yi

Abstract readMeta-Analysis
In one paragraph

Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Preoperative cervical extension range of motion and C7 preservation as predictors of axial symptoms following laminoplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ke ZhangGraduate School of Beijing, University of Chinese Medicine, Chaoyang, Beijing, 100029, China.
Zhencheng XiongDepartment of Orthopedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Yuhao ZhangGraduate School of Beijing, University of Chinese Medicine, Chaoyang, Beijing, 100029, China.
Ziyi ZhuangGraduate School of Beijing, University of Chinese Medicine, Chaoyang, Beijing, 100029, China.
Sizhen ZhanDepartment of Spine Surgery, China-Japanese Friendship Hospital, Chaoyang, Beijing, 100029, China.
Mingsheng TanDepartment of Spine Surgery, China-Japanese Friendship Hospital, Chaoyang, Beijing, 100029, China.
Ping YiDepartment of Spine Surgery, China-Japanese Friendship Hospital, Chaoyang, Beijing, 100029, China. CJFH_YPSpine@163.com.

Funding

China-Japan Friendship Hospital High-level Hospital Clinical Operating Expenses Specialized Clinical Research Project 2022-NHLHCRF-LX-02
6 · The paper itself

Abstract

backgroundAxial symptoms are a frequent complication after posterior cervical spine surgery.While literature has documented risk factors for these symptoms, they are still debated. This study's objective was to explore the risk elements associated with axial symptoms following posterior cervical spine surgery.

methodsOur search encompassed The Cochrane Library, PubMed, Embase, and web of science databases, focusing on studies documenting complications related to cervical laminectomy and laminoplasty. In every study included, we documented axial symptom occurrences and computed Odds Ratios (ORs), 95% confidence intervals (Cls), Q values, and 12 values.

resultsNineteen different studies were finally included, and a summary of the key risk and protective factors identified in the included studies is provided below: preoperative neck pain (OR = 2.22,95%CI (1.48,3.33), P = 0.0001), facet joint destruction(OR = 2.32,95%CI (1.59,3.39),P < 0.0001), C2involvement(OR = 3.78,95%CI(2.04,7.01), P < 0.0001),C7spinous process (muscle) destruction (OR = 3.38,95%CI (1.13,10.08),P = 0.03), conventional posterior cervical spine surgery (OR = 6.18,95%CI (2.43,15.69),P = 0.0001) protective factors were as follows: Increase range of motion after cervical spine surgery (OR = 0.64,95%CI (0.44,0.92), P = 0.02), enlargement of the preoperative C2-7 Cobb angle (OR = 0.57,95%CI(0.39,0.82),P = 0.003).

conclusionPreoperative neck pain, facet joints destruction, C7 spinous process(muscle)destruction, conventional posterior cervical spine surgery and C2 involvement were risk factors for postoperative axial symptoms after posterior cervical spine surgery, and a larger preoperative C2-C7 Cobb angle and increased postoperative cervical range of motion were protective factors for postoperative axial symptoms, however, gender, age, operation time, JOA score, C2-7 SVA, blood loss, and types of disease were not associated with postoperative axial symptoms. Considering the scarce volume of research available, this inference demands careful interpretation and necessitates expanded studies.

Indexed as

Cervical VertebraeLaminectomyLaminoplastyPostoperative ComplicationsHumansNeck PainRisk FactorsAxial symptomsCervical spine surgeryMeta-analysisRisk factors

Identifiers

PMID40841893
PMCPMC12369160

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.