ArticleEquine veterinary journal2026
Flow-controlled expiration improves gas exchange in anaesthetised horses undergoing orthopaedic surgery.
Article in Equine veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Flow-controlled expiration improves gas exchange in anaesthetised horses undergoing orthopaedic surgery.Equine veterinary journal · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundFlow-controlled expiration (FLEX) has been shown to significantly enhance oxygenation in horses under laboratory conditions.
objectiveThis study aims to corroborate these findings by evaluating the effects of FLEX on gas exchange in a randomised clinical trial involving a large population of clinical horses undergoing orthopaedic surgery. STUDY
designProspective randomised clinical trial.
methodsA total of 406 healthy adult horses scheduled for elective orthopaedic procedures were recruited for this prospective clinical trial. Horses were randomly assigned to FLEX or VCV (volume-controlled ventilation) groups in dorsal (VCV-D and FLEX-D) or lateral recumbency (VCV-L and FLEX-L). Arterial blood gases were measured at 30, 75, and 120 min post-induction to assess arterial oxygenation (arterial partial pressure of oxygen to inspired fraction of oxygen ratio, PaO
resultsHorses ventilated with FLEX showed significantly higher PaO MAIN LIMITATIONS: Anaesthesia protocols were not standardised; anaesthetists were not masked to the intervention of interest, and findings may not be generalisable to other patient populations.
conclusionsThese results confirm previous laboratory findings, demonstrating that FLEX improves oxygenation, ventilation-perfusion matching, and respiratory mechanics compared to VCV in a large clinical population of anaesthetised horses.
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