Evidence map›Paper›PMID 40841788›Full record

ArticleInternational journal of legal medicine2025

Assessment of a microhaplotype panel for human identification and ancestry inference in Brazil.

Luciellen Davila Giacomel Kobachuk, Vítor Matheus Soares Moraes, Thássia Mayra Telles Carratto, Letícia Marcorin, Aguinaldo Luiz Simões, Heather L Norton, Esteban J Parra, Erick C Castelli, Celso Teixeira Mendes-Junior

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Article in International journal of legal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luciellen Davila Giacomel Kobachuk *Faculdade de Medicina de Ribeirão Preto/USP, Departamento de Genética, Ribeirão Preto, São Paulo, Brazil. luciellengiacomel@usp.br.
Vítor Matheus Soares MoraesFaculdade de Medicina de Ribeirão Preto/USP, Departamento de Genética, Ribeirão Preto, São Paulo, Brazil.
Thássia Mayra Telles CarrattoFaculdade de Filosofia, Ciências e Letras de Ribeirão Preto/USP, Departamento de Química, Laboratório de Pesquisas Forenses e Genômicas, Ribeirão Preto, São Paulo, Brazil.
Letícia MarcorinFaculdade de Medicina de Ribeirão Preto/USP, Departamento de Genética, Ribeirão Preto, São Paulo, Brazil.
Aguinaldo Luiz SimõesFaculdade de Medicina de Ribeirão Preto/USP, Departamento de Genética, Ribeirão Preto, São Paulo, Brazil.
Heather L NortonDepartment of Anthropology, University of Cincinnati, Cincinnati, OH, USA.
Esteban J ParraDepartment of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.
Erick C CastelliPathology Department, School of Medicine, São Paulo State University - Unesp, Botucatu, São Paulo, Brazil.
Celso Teixeira Mendes-Junior *Faculdade de Medicina de Ribeirão Preto/USP, Departamento de Genética, Ribeirão Preto, São Paulo, Brazil. ctmendes@ffclrp.usp.br.

Funding

CAPES-PROCAD 88881.516238/2020-01CAPES-PROCAD 88887.516236/2020-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/15447-0National Institute of Justice 2013-DN-BX-K011Natural Sciences and Engineering Research Council of Canada Natural Sciences and Engineering Research Council of CanadaResearch fellowship from CNPq/Brazil 307031/2022-5Research fellowship from CNPq/Brazil 310016/2022-3
6 · The paper itself

Abstract

Microhaplotypes (MHs) comprise multiple single nucleotide polymorphisms (SNPs) in DNA segments of up to 300 bp in length. These SNP combinations result in numerous allelic variations (i.e., haplotypes). They are an emerging type of genetic marker with the potential to be an alternative to Short Tandem Repeats (STRs), Single Nucleotide Polymorphisms (SNPs), and Insertion/deletion polymorphisms (InDels) in population genetic studies and forensic cases involving degraded DNA or mixed contributors. This study is the first to evaluate a microhaplotype panel in an admixed Brazilian population. We assessed 130 MH markers in 344 individuals from Ribeirão Preto (State of São Paulo, Brazil) regarding their human identification and ancestry prediction application. DNA was extracted, and samples were genotyped using the Infinium Multi-Ethnic Global-8 array (MEGA) Kit (Illumina). The Sanger and Michigan imputation tools inferred SNPs missing in the MEGA assay. The linkage disequilibrium analysis indicated that 108 out of the 128 microhaplotypes behave independently at a population level, and the combined match probability for these 108 MHs was 4.4 × 10

Indexed as

EthnicityGenetics, PopulationHaplotypesPolymorphism, Single NucleotideRacial GroupsBrazilDNA FingerprintingGene FrequencyGenetic MarkersGenotypeHumansLinkage DisequilibriumMicrosatellite RepeatsGenetic MarkersAdmixtureBrazilian populationForensic geneticsForensic parametersMicrohaplotypes (MH)Population structure

Identifiers

PMID40841788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.