Article in Gene therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Xingle Zhao *Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0002-3992-2139
Hongen Xu *Precision Medicine Center, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-7895-0899
Chengyu Lian *Precision Medicine Center, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.
Shousen HuDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yue ZhaoPrecision Medicine Center, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.
Jia WangDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Rongqun ZhaiDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mihuan YangDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yuanjing ZhangDepartment of Cardiology, The 7th People's Hospital of Zhengzhou, Zhengzhou, China.
Wei LuDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. luwei611@zzu.edu.cn.ORCID 0000-0002-6858-196X
Wenxue TangThe Research and Application Center of Precision Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China. twx@zzu.edu.cn.
Liang WangDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. wangliang@zzu.edu.cn.ORCID 0000-0003-1555-7277
Funding
China Postdoctoral Science Foundation 2024M752977National Natural Science Foundation of China (National Science Foundation of China) 82371160
6 · The paper itself
Abstract
Vesicular glutamate transporter 3 (VGLUT3) is prominently expressed in the inner hair cells of the cochlea, playing a vital role in auditory signal transmission to the brain. Previous studies have shown that Vglut3 gene knockout in mice causes severe sensorineural hearing loss without affecting hair cell integrity. However, the cochlear structure of the aged Vglut3
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Gene therapy restores auditory function and rescues damaged inner hair cells in an aged Vglut3 knockout mouse model. · full record | OpenQuestion