ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026
Hearing and early life adversity: effects of developmental stress on sensory processing.
Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Early life visceral stress induces auditory brainstem sensitization and cochlear proteomic alterations in a rat model of irritable bowel syndrome.Neurobiology of stress · 2026Article
- Early Auditory Stimulation, Not Device Type: Comparable Cortical Maturation in Children Using Cochlear Implants or Hearing Aids.Children (Basel, Switzerland) · 2026Article
- Characterizing behavioral effects of early-life stress in an animal model of auditory processing.Physiology & behavior · 2026Article
- Developmental and early-life stress-induced effects on 5-HTNeurobiology of stress · 2026Article
- Trajectories of mental health and mental illness: where we are now and where we go next.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Developmental and Early-Life Stress-Induced Effects on 5-HTbioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In children, early hearing loss can cause prolonged difficulty with auditory perception and language processing. Yet children with hearing loss are at greater risk of long-term language, cognitive, and socioemotional deficits when raised with environmental challenges that are stressful, such as low socio-economic status. The neural circuits underlying language and auditory processing are shaped by auditory experience over the course of development, allowing listeners to make sense of environmental sounds including speech. Evidence is accumulating from work in animal models that these sensory circuits are also affected by adverse stressful experiences early in life. Recent experiments indicate that stress can exacerbate sensory deficits caused by developmental hearing loss. These effects are driven by shifts in mechanisms underlying developmental plasticity, as well as by consequences of altered activity of the hypothalamic-adrenal-pituitary (HPA) stress axis. Viewed through an interdisciplinary lens, the research reviewed here suggests that some of the challenges experienced by children with hearing loss may be intensified by early life adversity and ameliorated by interventions that target both sensory deprivation and stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.