ArticleScientific reports2025
A study on the correlation between pregnancy risk factors and birth outcomes.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Maternal and Neonatal Outcomes in Very Young Adolescent Pregnancies: A Single-Centre Retrospective Observational Study in Brașov, Romania.Healthcare (Basel, Switzerland) · 2026Article
- Impact of early pregnancy body mass index and gestational weight gain on birth outcomes: Findings from a pregnancy cohort in South Delhi, India.PLOS global public health · 2026Article
- Bisphenol exposure in preterm neonates: a cohort study with measurements at admission and discharge in a neonatal intensive care unit in Ankara, Türkiye.BMC pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Adverse birth outcomes-including low birth weight (LBW, < 2500 g), preterm birth (PTB, < 37 weeks), and intrauterine growth abnormalities-remain major global public health challenges, particularly in low- and middle-income countries. Although maternal body mass index (BMI) and gestational weight gain (GWG) are established risk factors in Western populations, their interactions with metabolic and sociodemographic factors in Asian cohorts, particularly within China's rapidly urbanizing populations, warrant further investigation. This prospective cohort study analyzed 1,026,294 singleton pregnancies (2012-2018) from the Liaoning Maternal and Child Health Information System. Using multivariate logistic regression models, we calculated adjusted risk ratios (RR) with 95% confidence intervals (CI) to evaluate associations between prenatal exposures… and birth outcomes: low birth weight (LBW), macrosomia (> 4000 g), Small-for-gestational-age (SGA, < 10th percentile), Large-for-gestational-age (LGA, > 90th percentile), PTB. Pre-pregnancy underweight (RR = 1.58, 95% CI 1.47-1.70), insufficient gestational weight gain (RR = 1.44, 95% CI 1.36-1.53), and preeclampsia (RR = 3.61, 95% CI 3.18-4.10) were strongly associated with low birth weight. For SGA, pre-pregnancy underweight (RR = 1.68, 95% CI 1.62-1.74) and insufficient GWG (RR = 1.40, 95% CI 1.29-1.51) were key predictors. Conversely, pre-pregnancy obesity (RR = 2.79, 95% CI 2.72-2.85) and excessive GWG (RR = 2.15, 95% CI 2.07-2.23) elevated macrosomia risk. PTB was strongly associated with pre-pregnancy obesity (RR = 1.29, 95% CI 1.25-1.33), assisted reproductive conception (RR = 3.39, 95% CI 3.01-3.83), and early-pregnancy hyperglycemia (RR = 1.19, 95% CI 1.15-2.22). Pre-pregnancy BMI, gestational weight gain (GWG), hypertensive disorders, and metabolic markers (e.g., fasting glucose, hemoglobin) constitute critical modifiable determinants of adverse birth outcomes. These findings quantify region-specific risk thresholds (e.g., 38.1% pre-pregnancy overweight/obesity vs. national 24.8%, Liaoning macrosomia 11.62% vs. national 8.9%) to prioritize GWG monitoring and metabolic screening in Northeast China's urban transition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.