Evidence map›Paper›PMID 40841616›Full record

ArticleBMC urology2025

Financial toxicity in lower urinary tract symptoms amongst men.

Wilson Sui, Pablo Suarez, Heiko Yang, Maria Camila Velasquez Escobar, Feres Camargo Maluf, Taylor Hall, Sultan Al Azzawi, Lavanya Gupta, Thomas Chi

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In one paragraph

Article in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wilson SuiDepartment of Urology, University of Michigan Medical School, 1500 E Medical Center Dr, Ann Arbor, MI, 48109, USA. Wilsonsi@med.umich.edu.
Pablo SuarezDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Heiko YangDepartment of Urology, University of Colorado, Aurora, CO, USA.
Maria Camila Velasquez EscobarDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Feres Camargo MalufDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.
Taylor HallDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Sultan Al AzzawiDepartment of Urology, University of California San Francisco, San Francisco, CA, USA.
Lavanya GuptaUniversity of California Berkeley, Berkeley, CA, USA.
Thomas ChiDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFinancial toxicity (FT), first reported in oncologic patients and generally defined as harm to patients caused by the cost of treatment, is less well described in non-malignant urology. In chronic conditions related to lower urinary tract symptoms (LUTS), such as BPH, treatment costs may result in a significant substantial burden. The goal of this study was to characterize the association between FT and LUTS.

methodsA cross-sectional web-based survey was administered to a random sample of adult men through a national registry of volunteers (ResearchMatch). Disease-specific information, validated symptom scores, and an 11-item measure of LUTS-related financial toxicity were used to characterize participants. Multivariable logistic regression was performed to identify predictors of financial toxicity.

resultsA total of 294 respondents with a self-reported history of BPH-associated LUTS were included, 41% of whom met the criteria for financial toxicity. Men with FT had worse LUTS symptom scores across all measures (p < 0.001). The presence of stress, urge, or mixed incontinence was significantly higher in men with FT (52% vs. 8%, 46% vs. 15%, and 36% vs. 5% respectively; p < 0.001). Men with FT spent more out-of-pocket on incontinence products than those without FT (p < 0.001). On multivariable analysis, mixed incontinence was a predictor of FT (OR 3.233, 95% CI 1.15–9.084).

conclusionTwo of five men with LUTS met the criteria for financial toxicity. These men had worse urinary symptom scores, higher rates of all types of incontinence, and higher out-of-pocket costs for incontinence products.

Indexed as

Cost of IllnessLower Urinary Tract SymptomsAgedCross-Sectional StudiesHumansMaleMiddle AgedProstatic HyperplasiaFinancial stressHealth expendituresLower urinary tract symptomsProstatic hyperplasiaUrinary incontinence

Identifiers

PMID40841616
PMCPMC12372289

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