Evidence map›Paper›PMID 40841592›Full record

ArticleSurgical endoscopy2025

Short- and long-term outcomes of laparoscopic endoscopic cooperative surgery for duodenal neoplasms: a retrospective single-center study.

Sho Sekiya, Toshihiro Kushibiki, Yuki Okawa, Mamoru Miyasaka, Daisuke Saikawa, Koichi Teramura, Satoshi Hayashi, Yoshinori Suzuki, Masaya Kawada, Yo Kawarada and 5 more

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Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sho SekiyaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan. sho.sekiya.729@gmail.com.ORCID http://orcid.org/0000-0001-9927-5028
Toshihiro KushibikiDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Yuki OkawaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Mamoru MiyasakaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Daisuke SaikawaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Koichi TeramuraDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Satoshi HayashiDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Yoshinori SuzukiDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Masaya KawadaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Yo KawaradaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Tetsuya SumiyoshiDepartment of Gastroenterology, Tonan Hospital, Sapporo, Japan.
Shuji KitashiroDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Kichizo KagaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Shunichi OkushibaDepartment of Surgery, Tonan Hospital, North‑4, West‑7, Chuo‑ku, Sapporo, 060‑0004, Japan.
Satoshi HiranoDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-ampullary duodenal tumors are relatively rare; however, advancements in esophagogastroduodenoscopy have improved their detection. Endoscopic resection is effective for treating adenomas and early-stage cancers without lymph node involvement. However, challenges include assessing tumor invasion depth, achieving complete resection, and managing postoperative complications such as delayed perforation. Consequently, laparoscopic endoscopic cooperative surgery (D-LECS) was introduced, but data on its long-term outcomes remain limited.

methodsThis retrospective study reviewed 18 cases of D-LECS performed between June 2016 and October 2024 at Tonan Hospital. Included patients had non-ampullary duodenal tumors-adenoma, mucosal adenocarcinoma, or neuroendocrine neoplasms-without lymph node involvement. Surgical outcomes, complications, and follow-up data were analyzed.

resultsThe median patient age was 65.5 years, and 14 patients were male. Tumors were located in the first (4 cases), second (11 cases), and third (3 cases) portions of the duodenum. The median operative time was 233 min, longer in the reinforcement after endoscopic submucosal dissection group than in the full-thickness resection group (289 vs. 221 min, P = 0.37). A Clavien-Dindo grade ≥ 3a complication occurred only in the first case, involving delayed perforation. The median hospital stay was 12 days. En-bloc and R0 resection rates were 83.3 and 92.9%, respectively. No long-term complications, including stricture or recurrence, were observed over a median follow-up of 37 months.

conclusionsD-LECS demonstrated favorable short- and long-term outcomes for non-ampullary duodenal tumors, with high en-bloc and R0 resection rates. These findings suggest that D-LECS is a viable treatment option for selected duodenal tumors.

Indexed as

AdenocarcinomaAdenomaDuodenal NeoplasmsEndoscopic Mucosal ResectionLaparoscopyNeuroendocrine TumorsAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesD-LECSEndoscopic submucosal dissectionLaparoscopic endoscopic cooperative surgeryNon-ampullary duodenal tumors

Identifiers

PMID40841592

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.