Evidence map›Paper›PMID 40841446›Full record

ArticleSurgery today2026

A multicenter trial evaluating the short-term outcomes of intracorporeal versus extracorporeal anastomosis in laparoscopic colectomy for overweight and obese patients with colon cancer: a secondary analysis of the ICAN study.

Emi Ota, Jun Watanabe, Hirokazu Suwa, Keitaro Tanaka, Tomohiro Yamaguchi, Hiroki Hamamoto, Atsushi Nishimura, Fumihiko Fujita, Heita Ozawa, Kenji Kobayashi and 3 more

Abstract readMulticenter StudyComparative Study
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In one paragraph

Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Emi OtaDepartment of Surgery, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Jun WatanabeDepartment of Colorectal Surgery, Kansai Medical University, 2-5-1, Shin-machi, Hirakata, Osaka, 573-1010, Japan. watanabj@hirakata.kmu.ac.jp.ORCID http://orcid.org/0000-0002-7187-3664
Hirokazu SuwaDepartment of Surgery, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Keitaro TanakaDepartment of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Tomohiro YamaguchiDepartment of Gastroenterological Surgery, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Hiroki HamamotoDepartment of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Atsushi NishimuraDepartment of Surgery, Institute of Gastroenterology, Nagaoka Chuo General Hospital, Niigata, Japan.
Fumihiko FujitaDepartment of Surgery, Kurume University School of Medicine, Fukuoka, Japan.
Heita OzawaDepartment of Colorectal Surgery, Tochigi Cancer Center, Utsunomiya, Japan.
Kenji KobayashiDepartment of Gastroenterological Surgery, Kariya Toyota General Hospital, Kariya, Japan.
Tomoaki OkadaDepartment of Surgery, Osaka Red Cross Hospital, Osaka, Japan.
Yukitoshi TodateDepartment of Surgery, Southern Tohoku General Hospital, Koriyama, Japan.
Takeshi NaitohDepartment of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe safety and benefits of intracorporeal anastomosis (ICAN) in overweight and obese colon cancer patients remain unclear. This study aimed to evaluate the short-term outcomes of ICAN compared to extracorporeal anastomosis (ECAN) in this population.

methodsThis nationwide multicenter retrospective cohort study included 46 institutions. Body mass index (BMI) ≥ 25 kg/m

resultsBetween January 2020 and December 2021, 361 patients were analyzed (ICAN, n = 191; ECAN, n = 170). ICAN was associated with a longer operative time (252 vs. 232 min, p < 0.001), but significantly less blood loss (5 vs. 15.5 ml, p < 0.001) and a shorter wound length (4 vs. 5 cm, p < 0.001). There were no significant differences in the intraoperative (1.6 vs. 1.8%) or postoperative complication rates (9.4 vs. 7.6%). The time to first stool passage was shorter in the ICAN group (3 (IQR 2-4) vs. 3 (IQR 3-5) days, p < 0.001).

conclusionsICAN is safe and beneficial for overweight and obese patients undergoing laparoscopic colectomy, offering reduced blood loss, smaller incisions, and a faster bowel recovery.

trial registrationThis study was registered in the UMIN Clinical Trials Registry System in 2022 (UMIN000047994).

Indexed as

AdenocarcinomaAnastomosis, SurgicalColectomyColonic NeoplasmsLaparoscopyObesityOverweightAgedBlood Loss, SurgicalBody Mass IndexCohort StudiesFemaleHumansMaleMiddle AgedOperative TimeColon cancerIntracorporeal anastomosisLaparoscopic colectomyObeseOverweight

Identifiers

PMID40841446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.