Evidence map›Paper›PMID 40840497›Full record

Trial reportKlinische Padiatrie2026

The effect of anti-nausea wristbands and STW-5 in children suffering from dyspepsia - a randomized double-blind placebo-controlled pilot-study.

Corinne Légeret, Sebastian Ludyga, Muriel D'Aujourdhui, Selina Schneider, Sarah Hagmann, Annemarie Acket, Henrik Köhler, Raoul Furlano

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Klinische Padiatrie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Corinne LégeretPediatric Gastroenterology, University Childrens Hospital Basel, Basel, Switzerland.ORCID 0000-0001-6972-542X
Sebastian LudygaDepartment of Sports, Movement and Health, University of Basel, Basel, Switzerland.
Muriel D'AujourdhuiMedical Faculty, University of Basel, Basel, Switzerland.
Selina SchneiderMedical Faculty, University of Basel, Basel, Switzerland.
Sarah HagmannMedical Faculty, University of Basel, Basel, Switzerland.
Annemarie AcketMedical Faculty, University of Basel, Basel, Switzerland.
Henrik KöhlerChildren's Hospital, Kantonsspital Aarau, Aarau, Switzerland.
Raoul FurlanoPediatric Gastroenterology, University Childrens Hospital Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Functional dyspepsia (FD) is common in children and refers to discomfort in the epigastric/duodenal region, which cannot be explained by structural or biochemical abnormalities. Since the pathophysiology is still not fully understood, no guidelines in terms of treatment do exist. Aim: The aim of this study was to compare the therapeutical effect of plant extracts (STW-5) and acupressure in children with functional dyspepsia. Methods: This is a randomized, double-blind placebo-controlled trial. Before and after the allocated intervention of four weeks, participants had to fill in a cross-cultural validated questionnaire consisting of 52 questions to assess quality of life, as well as the extent of their discomfort (using a standardized visual analog scale (VAS)). Results: 33 patients were included in the study: 12 male and 21 female with an average age of 12.09 years (range: 7-17 years). Symptoms improved after four weeks of intervention in most treatment-groups: By 68% in children, who received STW-5, by 40% in the wristband (WB)- group and by 35% in the wrist-band-Placebo-group (WBPL). Patients receiving STW-5- Placebo showed even an increase of symptoms. Discussion: This double-blind, placebo-controlled pilot study showed, that STW-5 and/or anti-nausea wristbands are a cheap and effective option to treat children and teenagers suffering from functional dyspepsia.

Indexed as

AcupressureDyspepsiaNauseaPhytotherapyPlant ExtractsAdolescentChildDouble-Blind MethodFemaleHumansMalePilot ProjectsQuality of LifePlant Extracts

Identifiers

PMID40840497
PMCPMC13585443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.