Evidence map›Paper›PMID 40840288›Full record

ArticlePoultry science2025

Unlocking growth potential in Wenchang chickens: A 21 K genotyping array for trait-associated structural variations.

Chong Wang, Chulong Wu, Chen Peng, Anhong Chen, Yuelang Zhang, Dongyou Yu, Lihong Gu, Zhengguang Wang, Pengju Zhao

Abstract read
In one paragraph

Article in Poultry science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chong WangHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: 12317021@zju.edu.cn.
Chulong WuHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: 2900198173@qq.com.
Chen PengHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: 22217072@zju.edu.cn.
Anhong ChenCollege of Animal Science & Technology, Guangxi University, Nanning, Guangxi 530004, PR China. Electronic address: cah1831485169@163.com.
Yuelang ZhangHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: zhangyuelang@zju.edu.cn.
Dongyou YuHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: dyyu@zju.edu.cn.
Lihong GuInstitute of Animal Science & Veterinary Medicine, Hainan Academy of Agricultural Sciences, Haikou, Hainan 570100, PR China. Electronic address: nil2008@yeah.net.
Zhengguang WangHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: wzhguang68@zju.edu.cn.
Pengju ZhaoHainan Institute, Zhejiang University, Sanya 572000, PR China; College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China. Electronic address: zhaopengju2014@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the poultry industry has embraced genome-wide assisted breeding techniques for broiler production, focusing primarily on single nucleotide polymorphisms (SNPs). However, the potential of genomic structural variations (SVs) in broiler traits remains largely unexplored due to cost and technology limitations. We developed a new chicken 21 K SV genotyping array and assessed its performance on 303 Wenchang chickens. Our evaluation showed a 99.20 % call rate with 57.13 % polymorphism across all microarray loci that identified SVs within the Wenchang chicken population. Genome-wide association studies (GWAS) of these SVs identified five significant variants associated with economically important traits, along with growth and development-related candidate genes including PLXAN4, ACBD3, and RNASET2. These findings demonstrate the value of SV-based approaches for improving genetic selection methods and enhancing productivity in poultry breeding programs. Our results show that high-quality 21 K SV genotyping arrays have significant potential for poultry breeding applications.

Indexed as

ChickensGenotyping TechniquesAnimalsBreedingGenome-Wide Association StudyGenotypePolymorphism, Single NucleotideChickenGWASPoultry breedingStructural variationSV genotyping array

Identifiers

PMID40840288
PMCPMC12396430

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.