Evidence map›Paper›PMID 40840120›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2025

Effects of Δ

Lawrence M Carey, Lindsey K Galbo-Thomma, David R Maguire, Charles P France

Abstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lawrence M CareyDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Addiction Research, Treatment & Training Center of Excellence, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Lindsey K Galbo-ThommaDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Addiction Research, Treatment & Training Center of Excellence, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
David R MaguireDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Addiction Research, Treatment & Training Center of Excellence, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Charles P FranceDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Addiction Research, Treatment & Training Center of Excellence, University of Texas Health Science Center at San Antonio, San Antonio, Texas; Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas. Electronic address: france@uthscsa.edu.

Funding

DISCRIMINATIVE STIMULUS OF OPIOID WITHDRAWALR01DA005018 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FRANCE, CHARLES P · 1988 to 2025
$8.8M
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
Cannabidiol and buprenorphine: A poly-pharmacy approach to treat opioid use disorderF32DA063281 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lindsey Galbo Thomma · 2025 to 2026
$92k
Cannabinoid type 2 receptors as a therapeutic target for substance use disordersF32DA057804 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CAREY IV, LAWRENCE MICHAEL · 2023 to 2023
$8k
NIDA NIH HHS F32 DA057804NIDA NIH HHS F32 DA063281NIDA NIH HHS L70 DA061529NIDA NIH HHS R01 DA005018NIDA NIH HHS T32 DA031115
6 · The paper itself

Abstract

The mu-opioid receptor agonists methadone and buprenorphine are effective for treating opioid use disorder (OUD); however, both drugs are diverted and misused and withdrawal signs can emerge when treatment is tapered or discontinued. Mu-opioid and cannabinoid type 1 receptors are colocalized in several brain regions, and cannabinoids have been proposed as potential treatments for opioid withdrawal. This study tested Δ

Indexed as

Behavior, AnimalCannabidiolDronabinolMorphineSubstance Withdrawal SyndromeAnimalsBlood PressureClonidineHeart RateMacaca mulattaMaleCannabidiolClonidineDronabinolMorphineCannabidiolOpioid withdrawalRhesus monkeyΔ(9)-Tetrahydrocannabinol

Identifiers

PMID40840120
PMCPMC12597650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.