Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors.
Jueun JeonCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Q John LiuAccure Health Inc., Cambridge, Massachusetts 02139, United States.
Hyunkyung WooCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0003-1332-6029
Isabel BarthCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
Yoonjeong ChoiCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.
L Jessica SangAccure Health Inc., Cambridge, Massachusetts 02139, United States.ORCID 0009-0004-2508-1000
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.ORCID 0000-0002-0087-0909
Funding
Expanding early cancer detection with high throughput OCEANA - Ovarian Cancer Exosome Analysis with Nanoplasmonic ArrayU01CA284982 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Cesar M Castro, Hakho Lee · 2023 to 2026
$3.7M
Imaging and Liquid Biopsy for Glioma Diagnosis and Treatment MonitoringR01CA239078 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BALAJ, LEONORA, LEE, HAKHO · 2020 to 2024
$3.1M
High-throughput Phenotyping of iPSC-derived Airway Epithelium by Multiscale Machine Learning MicroscopyR01HL163513 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI Hakho Lee, Kwonmoo Lee · 2023 to 2026
$3.1M
Standardized Molecular Analyses of Glioma EVsR01CA237500 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CARTER, BOB S, LEE, HAKHO · 2020 to 2024
$3.0M
High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancerR01CA264363 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CASTRO, CESAR M, LEE, HAKHO · 2021 to 2024
$2.4M
Composing CODAs to cervical cancer screening through an integrated CRISPR and fluorescent nucleic acid approachU01CA279858 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Cesar M Castro, Hakho Lee · 2023 to 2026
$2.1M
3D Fourier Imaging System for High Throughput Analyses of Cancer OrganoidsR21CA267222 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2022 to 2024
$613k
Automated plasma EV-PDL1 analysis for cancer immunotherapyR43CA275548 · NCI · ACCURE HEALTH, INC. · PI SANG, LIYUN JESSICA · 2022 to 2022
Detecting protein biomarkers is critical in fundamental research and clinical investigations of extracellular vesicles (EVs). Despite the prevalent use of antibodies as recognition elements, their application is often limited by challenges such as cross-reactivity and inconsistent affinity. Here, we report designed nanobinders (DNBs) as a promising alternative for EV protein analysis. Our approach adopted recent advances in
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Computationally Designed Nanobinders as Affinity Ligands in Diagnostic and Therapeutic Applications. · full record | OpenQuestion