Evidence map›Paper›PMID 40839674›Full record

ArticlePLoS medicine2025

Cardiovascular-kidney-metabolic syndrome: A new frontier or simple rebranding?

Jennifer Manne-Goehler, Willem Daniel Francois Venter, Mohammed K Ali, Juan V A Franco

Abstract readComment
In one paragraph

Article in PLoS medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jennifer Manne-GoehlerDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0001-9295-0035
Willem Daniel Francois VenterEzintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
Mohammed K AliEmory Global Diabetes Research Center, Robert W. Woodruff Health Sciences Center, Emory University, Atlanta, Georgia, United States of America.ORCID https://orcid.org/0000-0001-7266-2503
Juan V A FrancoInstitute of General Practice, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.ORCID https://orcid.org/0000-0003-0411-899X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular-kidney-metabolic (CKM) syndrome is an emerging framework proposed by the American Heart Association for management of patients with cardio-metabolic multimorbidity. This novel framework offers several improvements over existing paradigms; however, it remains unclear whether it represents a new frontier, or a simple rebranding of known clinical principles.

Indexed as

Cardio-Renal SyndromeCardiovascular DiseasesMetabolic SyndromeAmerican Heart AssociationHumansPractice Guidelines as Topic

Identifiers

PMID40839674
PMCPMC12396749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.