Evidence map›Paper›PMID 40839183›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2025

Evaluation of Campylobacter fetus subspecies concentrations in commercial bovine reproductive vaccines.

Maria Eduarda Dias, Gabriela Merker Breyer, Silvia De Carli, Franciele Maboni Siqueira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Eduarda DiasLaboratório de Bacteriologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, 91540-000, RS, Brazil.
Gabriela Merker BreyerLaboratório de Bacteriologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, 91540-000, RS, Brazil.
Silvia De CarliLaboratório de Bacteriologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, 91540-000, RS, Brazil.
Franciele Maboni SiqueiraLaboratório de Bacteriologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, 91540-000, RS, Brazil. franciele.siqueira@ufrgs.br.ORCID http://orcid.org/0000-0001-7282-6117

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 305939/2022-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 420590/2018-8
6 · The paper itself

Abstract

Campylobacter fetus is an important etiological agent of reproductive infections in cattle, which can be managed through vaccination. Nevertheless, the efficacy of bovine reproductive vaccines against C. fetus remains uncertain due to the absence of standardized guidelines and variable vaccine formulations. Thus, this study aimed to quantify and compare C. fetus subsp. fetus (Cff) and C. fetus subsp. venerealis (Cfv) in six commercial reproductive vaccines current available in Brazil in 2022. We observed significant differences in the estimated number of genome copies of Cff and Cfv among the tested vaccines. Analysis of vaccine cost and antigen concentration revealed no direct correlation between price and C. fetus antigen concentration. These findings underscore the discrepancies in antigen titration among bovine reproductive vaccines and highlight the lack of informative labeling in current commercial products. Altogether, there is a pressing need for standardized guidelines for C. fetus vaccinal doses to ensure consistent bacterial loads and efficient immunization of the herds. Nevertheless, more studies regarding vaccine efficiency are required to ensure an appropriate immune response in cattle herds.

Indexed as

Bacterial VaccinesCampylobacter fetusCampylobacter InfectionsCattle DiseasesAnimalsAntigens, BacterialBrazilCattleFemaleVaccinationAntigens, BacterialBacterial VaccinesBovine abortionbovine genital campylobacteriosisCampylobacter fetus subspfetusreproductive diseasesVenerealis

Identifiers

PMID40839183
PMCPMC12660606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.