Evidence map›Paper›PMID 40839085›Full record

ArticleArchives of orthopaedic and trauma surgery2025

High-level activity and access to sport following lower limb amputation due to malignant musculoskeletal tumors versus trauma: a prospective comparative study.

Astrid Schenker, Sebastian I Wolf, Merkur Alimusaj, Cornelia Putz, Burkhard Lehner, Julia Block

Abstract readComparative Study
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Astrid SchenkerHeidelberg University Hospital, Heidelberg, Germany. astrid.schenker@med.uni-heidelberg.de.
Sebastian I WolfUniversity of Heidelberg, Heidelberg, Germany.
Merkur AlimusajHeidelberg University Hospital, Heidelberg, Germany.
Cornelia PutzHeidelberg University Hospital, Heidelberg, Germany.
Burkhard LehnerHeidelberg University Hospital, Heidelberg, Germany.
Julia BlockUniversity of Heidelberg, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with musculoskeletal tumors who undergo amputation show reduced physical function. To give these patients better expectations of their future physical capabilities and to enhance the evaluation and development of postoperative rehabilitation, we investigated high-level activity and access to sport using objective measurements and questionnaires. We then compared the results to those of amputees who had undergone amputation due to trauma. MATERIALS AND

methodsIn a prospective, monocentric study, we evaluated and correlated the results of the conventional mobility tests such as "timed-up-and-go" test (TUG), "2-Minute-Walk-Test" (2MWT), as well as the "10-Meter-Walk-Test" (10MWT) with a test for high-level activity. In this contribution, the Comprehensive High-Level Activity Mobility Predictor (CHAMP), originally developed for male servicemembers, was tested for feasibility in our cohort. We examined eleven patients who underwent amputation due to primary malignant bone or soft-tissue sarcomas and compared the results with ten patients who experienced traumatic amputation, along with seventeen patients in the healthy control group.

resultsPatients with lower leg amputations due to malignant musculoskeletal tumors exhibited superior outcomes in general mobility and high-level activity mobility compared to those with traumatic amputations. Using a questionnaire, we were able to demonstrate that patients suffering after amputation because of musculoskeletal tumor exhibited higher motivation and a greater sense of health and well-being compared to participants who had undergone traumatic amputation.

conclusionsThe CHAMP can be utilized as a complementary tool in the rehabilitation of amputees to objectively assess high-level mobility and to guide targeted training and therapeutic interventions.

Indexed as

Amputation, SurgicalAmputation, TraumaticBone NeoplasmsLower ExtremityReturn to SportSarcomaAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesYoung AdultAmputationCHAMPHigh-level activityOutcome measurementsRehabilitationSportsTumor amputations

Identifiers

PMID40839085
PMCPMC12370868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.