Evidence map›Paper›PMID 40838762›Full record

ArticleACS applied materials & interfaces2025

Au Bipyramids as NIR-II Contrast Agents for In Vivo Plant Imaging.

Luis D B Manuel, Debarati Basu, Mary Beth Rollins, Vinoin Devpaul Vincely, Pelham Keahey, Martin Villiger, Carolyn L Bayer, Paul F South, Kevin M McPeak

Abstract readComparative Study
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis D B ManuelGordon and Mary Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0002-9314-6396
Debarati BasuDepartment of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Mary Beth RollinsDepartment of Plant Pathology and Crop Physiology, Louisiana State University College of Agriculture, Baton Rouge, Louisiana 70803, United States.
Vinoin Devpaul VincelyDepartment of Biomedical Engineering, Tulane University, New Orleans, Louisiana 70118, United States.
Pelham KeaheyHarvard Medical School, Boston, Massachusetts 02115, United States.ORCID 0000-0002-9504-9696
Martin VilligerHarvard Medical School, Boston, Massachusetts 02115, United States.ORCID 0000-0003-3819-1271
Carolyn L BayerDepartment of Biomedical Engineering, Tulane University, New Orleans, Louisiana 70118, United States.ORCID 0000-0003-0947-6892
Paul F SouthDepartment of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Kevin M McPeakGordon and Mary Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0002-2766-104X

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

In vivo plant imaging is crucial for understanding plant biology and the influence of external factors on plant health. While exogenous contrast agents are widely used in animal bioimaging to enhance contrast, track flows, and provide molecular specificity, their application in plant tissue remains challenging and underexplored. Herein, we highlight the shortcomings of contrast agents in optical coherence tomography of plant tissue while demonstrating the successful use of Au bipyramids (AuBPs) as effective NIR-II contrast agents in photoacoustic imaging, enabling spatiotemporal flow tracking in live Buttercrunch lettuce over 5 days. Furthermore, rigorous plant health studies showed no adverse effects of the AuBPs on the physiological properties of Buttercrunch lettuce 7 days postinfiltration. The use of AuBPs as contrast agents in plant imaging, combined with the versatility of their surface chemistry, opens the possibilities for studies with molecular specificity.

Indexed as

Contrast MediaNanostructuresPlantsTomography, Optical CoherenceGoldPhotoacoustic TechniquesContrast MediaGoldcytotoxicitygold bipyramidsNIR-IIoptical coherence tomographyphotoacoustic imagingplantsplasmonic nanoparticlesspatiotemporal imaging

Identifiers

PMID40838762
PMCPMC12412101

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.