ArticleBiology of reproduction2026
Bovine uterine fluid lipidome parallels embryo and conceptus developmental milestones†.
Article in Biology of reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Influence of sire fertility on the metabolism of in vitro produced embryos.Reproduction & fertility · 2026Article
- Developmental origins of pregnancy loss in cattle.Animal reproduction · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
An optimal uterine luminal fluid (ULF) microenvironment is essential for successful pregnancy establishment and progression. Despite this, the specific factors influencing early embryo and conceptus (embryo and extra-embryonic structures) survival remain poorly understood. Lipid moieties dominate the ULF metabolome and are thought to play crucial roles in embryo and conceptus development. As such, we aimed to comprehensively profile the bovine ULF lipidome at four key times of the estrous cycle-Days 0, 7, 10, and 14. Our analysis identified 80 distinct lipids, which were categorized into 29 metabolic pathways. We observed significant (P ≤ 0.05) temporal variation in lipid abundance, with certain lipids uniquely present on specific days. Notably, carnitine derivatives exhibited pronounced changes in abundance throughout the cycle. These findings highlight the dynamic nature of ULF lipid composition and its potential influence on early reproductive events. We also discuss the implications of these results for enhancing both in vivo and in vitro embryo development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.