ArticlePM & R : the journal of injury, function, and rehabilitation2026
Associations among aerobic physical activity, mild traumatic brain injury history, and health-related quality of life in military service members and Veterans: A LIMBIC-CENC study.
Article in PM & R : the journal of injury, function, and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Impact of Physical Activity on Clinical Outcomes in Veterans Completing the VA's Traumatic Brain Injury Screening and Evaluation Program.The Journal of head trauma rehabilitation · 2026Article
- Holistic Performance Programming for mTBI Recovery in U.S. Military Tactical Athletes: A Narrative Review.Sports (Basel, Switzerland) · 2026Review
- Associations among aerobic physical activity, mild traumatic brain injury history, and health-related quality of life in military service members and Veterans: A LIMBIC-CENC study.PM & R : the journal of injury, function, and rehabilitation · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundMild traumatic brain injury (mTBI) is common among military service members. Moderate-to-vigorous aerobic exercise (MVAE) is a modifiable behavior with potential benefits for individuals following mTBI but is poorly understood for long-term mTBI health.
objectiveTo explore the associations between mTBI history and MVAE participation and appreciate their association with health-related quality of life (HR-QOL) among service members and Veterans.
methodsData from a larger study were used in these secondary cross-sectional analyses. Lifetime mTBI history (0, 1-2, 3+) was captured via validated structured interviews. Self-reported weekly MVAE (none, below, meeting, or ≥2 times the recommendation) was recorded from the Behavioral Risk Factor Surveillance System questionnaire. Participants' HR-QOL was self-reported via Traumatic Brain Injury-Quality of Life instrument and the Patient Health Questionnaire-9 (depression symptoms). Univariate mTBI history and MVAE associations were assessed via Pearson's chi-square and Kendall's Tau. Multivariable linear regression models with unstandardized beta values and 95% confidence intervals were fit for each HR-QOL questionnaire outcome, with current age, sex, and posttraumatic stress disorder symptoms as covariates (α = .05).
resultsAmong the 1995 participants (87.7% male; aged 41.7 ± 10.1 years), those meeting or exceeding (≥2 times) MVAE recommendations had significantly higher HR-QOL for fatigue, executive function, pain interference, resilience, social participation, and depression than the inactive MVAE group. Exceeding MVAE recommendations by ≥2 times was also significantly associated with better self-reported cognition - general concerns. Those who participated in exercise but didn't meet the MVAE recommendations had higher pain interference, social participation, and depression scores compared to the inactive group. More lifetime mTBIs were associated with worse HR-QOL across all domains. Level of MVAE participation was not dependent on mTBI history.
conclusionsMore MVAE was associated with better TBI-related HR-QOL regardless of mTBI history. MVAE is recommended for service members and Veterans due to these findings and previously reported health benefits.
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