Evidence map›Paper›PMID 40838476›Full record

ArticleTurkish journal of ophthalmology2025

Performance of ChatGPT-4 Omni and Gemini 1.5 Pro on Ophthalmology-Related Questions in the Turkish Medical Specialty Exam.

Mehmet Cem Sabaner, Zübeyir Yozgat

Abstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mehmet Cem SabanerKastamonu University Faculty of Medicine; Kastamonu Training and Research Hospital, Department of Ophthalmology, Kastamonu, Türkiye.ORCID 0000-0002-0958-9961
Zübeyir YozgatKastamonu University Faculty of Medicine; Kastamonu Training and Research Hospital, Department of Ophthalmology, Kastamonu, Türkiye.ORCID 0000-0001-5248-5562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the response and interpretative capabilities of two pioneering artificial intelligence (AI)-based large language model (LLM) platforms in addressing ophthalmology-related multiple-choice questions (MCQs) from Turkish Medical Specialty Exams. Materials and Methods: MCQs from a total of 37 exams held between 2006-2024 were reviewed. Ophthalmology-related questions were identified and categorized into sections. The selected questions were asked to the ChatGPT-4o and Gemini 1.5 Pro AI-based LLM chatbots in both Turkish and English with specific prompts, then re-asked without any interaction. In the final step, feedback for incorrect responses were generated and all questions were posed a third time. Results: A total of 220 ophthalmology-related questions out of 7312 MCQs were evaluated using both AI-based LLMs. A mean of 6.47±2.91 (range: 2-13) MCQs was taken from each of the 33 parts (32 full exams and the pooled 10% of exams shared between 2022 and 2024). After the final step, ChatGPT-4o achieved higher accuracy in both Turkish (97.3%) and English (97.7%) compared to Gemini 1.5 Pro (94.1% and 93.2%, respectively), with a statistically significant difference in English (p=0.039) but not in Turkish (p=0.159). There was no statistically significant difference in either the inter-AI comparison of sections or interlingual comparison. Conclusion: While both AI platforms demonstrated robust performance in addressing ophthalmology-related MCQs, ChatGPT-4o was slightly superior. These models have the potential to enhance ophthalmological medical education, not only by accurately selecting the answers to MCQs but also by providing detailed explanations.

Indexed as

Artificial IntelligenceClinical CompetenceEducational MeasurementEducation, Medical, GraduateOphthalmologyGenerative Artificial IntelligenceHumansTurkeyArtificial intelligenceChatGPT-4 omnie-learningGemini 1.5 Prolarge language modelmedical educationophthalmology

Identifiers

PMID40838476
PMCPMC12372544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.