SynthesisHaemophilia : the official journal of the World Federation of Hemophilia2025
Dental Management for People With Congenital Haemophilia: A Systematic Review of the Existing Dental Recommendations.
Synthesis in Haemophilia : the official journal of the World Federation of Hemophilia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence-based dental management strategies for individuals with congenital hemophilia: a systematic review.BMC oral health · 2026Pooled it
- Dental Management for People With Congenital Haemophilia: A Systematic Review of the Existing Dental Recommendations.Haemophilia : the official journal of the World Federation of Hemophilia · 2025Pooled it
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHaemophilia is the most common inherited bleeding disorder. Dental management for people with haemophilia (PwH) (both A and B) is challenging, as dental procedures may initiate bleeding episodes that may be difficult to control.
objectivesThis systematic review aimed to evaluate and summarize the existing dental guidelines that are proposed from various agencies/professional bodies, and so forth, for dental treatment procedures in PwH.
methodsA systematic electronic search on databases like Scopus, Medline, EMBASE, CINAHL, ProQuest and Web of Science was performed. The parameters evaluated were (a) clotting factor replacement therapy employed, (b) haemostatic agents, both local and systemic therapy and (c) dental procedural and pharmacological considerations that are recommended before, during, and after dental treatment procedures for people with mild, moderate and severe haemophilia. The dental treatment procedures included all minor and major procedures, including surgical extraction of wisdom teeth.
resultsA total of 11 guidelines were included for data extraction. The results indicated that all guidelines emphasized the importance of close collaboration among haematologists and dental professionals to ensure safe and effective dental treatment as a key component of comprehensive dental care. The various dental treatments (restorative, periodontal, orthodontic and prosthodontic treatments) and preventive aspects of oral health are detailed. Also, the amount of clotting factor replacement therapy for dental procedures, and pharmacological considerations recommended from the various professional organizations are discussed.
conclusionWell-designed large-scale research initiatives in dental management for PwH are necessary to understand the applicability and outcomes of such guidelines in clinical practice.
trial registrationREF/2024/01/077096.
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