ArticleFrontiers in psychiatry2025
Development and evaluation of LLM-based suicide intervention chatbot.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Applications, Challenges, and Future Directions of Large Language Models in Health Care Communication: Scoping Review.Journal of medical Internet research · 2026Article
- Are artificial intelligence chatbots safe for suicide risk assessment? A narratively synthesized review of current evidence.Global mental health (Cambridge, England) · 2026Review
- Generative AI in psychiatric education: balancing risks and benefits for responsible integration.Frontiers in psychiatry · 2026Article
- Cybersecurity and Privacy Risks of Generative AI Mental-Health Chatbots: A Systematic Review and Regulatory Framework.Journal of multidisciplinary healthcare · 2026Review
- Generative artificial intelligence in depression research: A bibliometric analysis of WoSCC-Indexed literature.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Suicide accounts for over 720,000 deaths globally each year, and many more individuals experiencing suicidal ideation; thus, implementing large-scale, effective suicide intervention is vital for reducing suicidal behaviors. Traditional suicide intervention methods are hampered by shortages of qualified practitioners, variability in clinical competence, and high service costs. This study leverages Large Language Models (LLMs) to develop an effective suicide intervention chatbot, which provides early, large-scale, rapid self-help interventions. Methods: First, according to existing psychological crisis intervention methods, we fine-tuned ChatGPT-4 via prompt engineering to develop a chatbot that promptly responds to the needs of individuals experiencing suicidal ideation. Then, we implemented a self-help web-based dialogue platform powered by this chatbot and conducted the evaluations of its usability and intervention efficacy. Results: We found that the self-help suicide intervention chatbot achieved high effectiveness and quality in terms of user interface operability, interaction experience, emotional support, intervention efficacy, safety and privacy, and overall satisfaction. Discussion: These findings demonstrate that the suicide intervention chatbot can provide effective emotional support and therapeutic intervention to a large cohort experiencing suicidal ideation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.