Evidence map›Paper›PMID 40838251›Full record

ArticleFrontiers in psychiatry2025

Development and evaluation of LLM-based suicide intervention chatbot.

Xueting Cui, Yun Gu, Hui Fang, Tingshao Zhu

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xueting CuiState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences (CAS), Beijing, China.
Yun GuState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences (CAS), Beijing, China.
Hui FangThe Fifth People's Hospital of Nanning, Nanning, China.
Tingshao ZhuState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences (CAS), Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Suicide accounts for over 720,000 deaths globally each year, and many more individuals experiencing suicidal ideation; thus, implementing large-scale, effective suicide intervention is vital for reducing suicidal behaviors. Traditional suicide intervention methods are hampered by shortages of qualified practitioners, variability in clinical competence, and high service costs. This study leverages Large Language Models (LLMs) to develop an effective suicide intervention chatbot, which provides early, large-scale, rapid self-help interventions. Methods: First, according to existing psychological crisis intervention methods, we fine-tuned ChatGPT-4 via prompt engineering to develop a chatbot that promptly responds to the needs of individuals experiencing suicidal ideation. Then, we implemented a self-help web-based dialogue platform powered by this chatbot and conducted the evaluations of its usability and intervention efficacy. Results: We found that the self-help suicide intervention chatbot achieved high effectiveness and quality in terms of user interface operability, interaction experience, emotional support, intervention efficacy, safety and privacy, and overall satisfaction. Discussion: These findings demonstrate that the suicide intervention chatbot can provide effective emotional support and therapeutic intervention to a large cohort experiencing suicidal ideation.

Indexed as

chatbotlarge language modelself-help psychological crisis interventionsuicidal ideationsuicide prevention and intervention

Identifiers

PMID40838251
PMCPMC12362262

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.