Evidence map›Paper›PMID 40838204›Full record

ArticleJournal of aging research2025

Examining the Cognitive Underpinnings of Functional Decline in Prodromal Alzheimer's Disease: Insights From the Details of Functions of Everyday Life (DoFEL) Scale.

Freddie O'Donald, Clara Calia, Mario A Parra

Abstract read
In one paragraph

Article in Journal of aging research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Freddie O'DonaldSchool of Health in Social Science, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0009-0009-6761-609X
Clara CaliaSchool of Health in Social Science, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0003-2505-6361
Mario A ParraSchool of Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.ORCID https://orcid.org/0000-0002-2412-648X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Available assessments for early-stage Alzheimer's disease (AD) identify neuropsychological and functional impairments, which rarely correlate in the early disease stages. The ability to bind information in memory declines in preclinical AD stages. However, it is unclear whether such cognitive deficits underlie functional impairment in prodromal AD stages. This study investigates whether incorporating memory binding, a function that is a sensitive cognitive marker for early-stage AD, into a functional assessment tool can reveal the cognitive underpinnings of daily activities. The Details of Function of Everyday Life (DoFEL) scale was revised, and its latent structure was explored through principal axis factoring in a nonclinical sample (

Indexed as

dementiaearly detectionfunctional assessmentmild cognitive impairmentvisual short-term memory binding

Identifiers

PMID40838204
PMCPMC12364600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.